OccuPeak: ChIP-Seq Peak Calling Based on Internal Background Modelling

ChIP-seq has become a major tool for the genome-wide identification of transcription factor binding or histone modification sites. Most peak-calling algorithms require input control datasets to model the occurrence of background reads to account for local sequencing and GC bias. However, the GC-cont...

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Bibliografiska uppgifter
Huvudupphovsmän: de Boer, Bouke A., van Duijvenboden, Karel, van den Boogaard, Malou, Christoffels, Vincent M., Barnett, Phil, Ruijter, Jan M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2014
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4061025/
https://ncbi.nlm.nih.gov/pubmed/24936875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0099844
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