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OccuPeak: ChIP-Seq Peak Calling Based on Internal Background Modelling
ChIP-seq has become a major tool for the genome-wide identification of transcription factor binding or histone modification sites. Most peak-calling algorithms require input control datasets to model the occurrence of background reads to account for local sequencing and GC bias. However, the GC-cont...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4061025/ https://ncbi.nlm.nih.gov/pubmed/24936875 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0099844 |
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