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Fever-induced QTc prolongation and ventricular arrhythmias in individuals with type 2 congenital long QT syndrome

Type 2 congenital long QT syndrome (LQT-2) is linked to mutations in the human ether a-go-go–related gene (HERG) and is characterized by rate-corrected QT interval (QTc) prolongation, ventricular arrhythmias, syncope, and sudden death. Recognized triggers of these cardiac events include emotional an...

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Detalhes bibliográficos
Main Authors: Amin, Ahmad S., Herfst, Lucas J., Delisle, Brian P., Klemens, Christine A., Rook, Martin B., Bezzina, Connie R., Underkofler, Heather A.S., Holzem, Katherine M., Ruijter, Jan M., Tan, Hanno L., January, Craig T., Wilde, Arthur A.M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2423868/
https://ncbi.nlm.nih.gov/pubmed/18551196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI35337
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