APOC3 deficiency: from mice to man

Por Hofker, Marten H
Publicado em 2010

Scavenging new insights into atherogenesis

Por de Winther, Menno P.J., Hofker, Marten H.
Publicado em 2000

Neutrophil-Derived Myeloperoxidase Aggravates Non-Alcoholic Steatohepatitis in Low-Density Lipoprotein Receptor-Deficient Mice

Por Rensen, Sander S., Bieghs, Veerle, Xanthoulea, Sofia, Arfianti, Evi, Bakker, Jaap A., Shiri-Sverdlov, Ronit, Hofker, Marten H., Greve, Jan Willem, Buurman, Wim A.
Publicado em 2012

Hematopoietic Npc1 mutation shifts gut microbiota composition in Ldlr(−/−) mice on a high-fat, high-cholesterol diet

Por Houben, Tom, Penders, John, Oligschlaeger, Yvonne, dos Reis, Inês A. Magro, Bonder, Marc-Jan, Koonen, Debby P., Fu, Jingyuan, Hofker, Marten H., Shiri-Sverdlov, Ronit
Publicado no Sci Rep (2019)

Specific immunization strategies against oxidized LDL: a novel way to reduce non-alcoholic steatohepatitis in mice

Por Bieghs, Veerle, van Gorp, Patrick J, Walenbergh, Sofie, Gijbels, Marion J, Verheyen, Fons, Buurman, Wim A, Briles, David E., Hofker, Marten H, Binder, Christoph J, Shiri-Sverdlov, Ronit
Publicado em 2012

The Copper Metabolism MURR1 Domain Protein 1 (COMMD1) Modulates the Aggregation of Misfolded Protein Species in a Client-Specific Manner

Por Vonk, Willianne I. M., Kakkar, Vaishali, Bartuzi, Paulina, Jaarsma, Dick, Berger, Ruud, Hofker, Marten H., Klomp, Leo W. J., Wijmenga, Cisca, Kampinga, Harm H., van de Sluis, Bart
Publicado em 2014

Internalization of Modified Lipids by CD36 and SR-A Leads to Hepatic Inflammation and Lysosomal Cholesterol Storage in Kupffer Cells

Por Bieghs, Veerle, Verheyen, Fons, van Gorp, Patrick J., Hendrikx, Tim, Wouters, Kristiaan, Lütjohann, Dieter, Gijbels, Marion J. J., Febbraio, Maria, Binder, Christoph J., Hofker, Marten H., Shiri-Sverdlov, Ronit
Publicado em 2012

Association between 9p21 genetic variants and mortality risk in a prospective cohort of patients with type 2 diabetes (ZODIAC-15)

Por Landman, Gijs WD, van Vliet-Ostaptchouk, Jana V, Kleefstra, Nanne, van Hateren, Kornelis JJ, Drion, Iefke, Groenier, Klaas H, Gans, Rijk OB, Snieder, Harold, Hofker, Marten H, Bilo, Henk JG
Publicado em 2012

Minor Xp21 chromosome deletion in a male associated with expression of duchenne muscular dystrophy, chronic granulomatous disease, retinitis pigmentosa, and McLeod syndrome

Por Francke, Uta, Ochs, Hans D., de Martinville, Bérengère, Giacalone, Joseph, Lindgren, Valerie, Distèche, Christine, Pagon, Roberta A., Hofker, Marten H., van Ommen, Gert-Jan B., Pearson, Peter L., Wedgwood, Ralph J.
Publicado em 1985

LDL Receptor Knock-Out Mice Are a Physiological Model Particularly Vulnerable to Study the Onset of Inflammation in Non-Alcoholic Fatty Liver Disease

Por Bieghs, Veerle, Van Gorp, Patrick J., Wouters, Kristiaan, Hendrikx, Tim, Gijbels, Marion J., van Bilsen, Marc, Bakker, Jaap, Binder, Christoph J., Lütjohann, Dieter, Staels, Bart, Hofker, Marten H., Shiri-Sverdlov, Ronit
Publicado em 2012

Polymorphisms of the TUB Gene Are Associated with Body Composition and Eating Behavior in Middle-Aged Women

Por van Vliet-Ostaptchouk, Jana V., Onland-Moret, N. Charlotte, Shiri-Sverdlov, Ronit, van Gorp, Patrick J. J., Custers, Anne, Peeters, Petra H. M., Wijmenga, Cisca, Hofker, Marten H., van der Schouw, Yvonne T.
Publicado em 2008

Trapping of oxidized LDL in lysosomes of Kupffer cells is a trigger for hepatic inflammation

Por Bieghs, Veerle, Walenbergh, Sofie M. A., Hendrikx, Tim, van Gorp, Patrick J., Verheyen, Fons, Damink, Steven W. Olde, Masclee, Ad A., Koek, Ger H., Hofker, Marten H., Binder, Christoph J., Shiri-Sverdlov, Ronit
Publicado em 2013

Cholesterol-Induced Hepatic Inflammation Does Not Underlie the Predisposition to Insulin Resistance in Dyslipidemic Female LDL Receptor Knockout Mice

Por Gruben, Nanda, Funke, Anouk, Kloosterhuis, Niels J., Schreurs, Marijke, Sheedfar, Fareeba, Havinga, Rick, Houten, Sander M., Shiri-Sverdlov, Ronit, van de Sluis, Bart, Kuivenhoven, Jan Albert, Koonen, Debby P. Y., Hofker, Marten H.
Publicado no J Diabetes Res (2015)

Nuclear COMMD1 Is Associated with Cisplatin Sensitivity in Ovarian Cancer

Por Fedoseienko, Alina, Wieringa, Hylke W., Wisman, G. Bea A., Duiker, Evelien, Reyners, Anna K. L., Hofker, Marten H., van der Zee, Ate G. J., van de Sluis, Bart, van Vugt, Marcel A. T. M.
Publicado no PLoS One (2016)

Blood-derived macrophages prone to accumulate lysosomal lipids trigger oxLDL-dependent murine hepatic inflammation

Por Houben, Tom, Oligschlaeger, Yvonne, Bitorina, Albert V., Hendrikx, Tim, Walenbergh, Sofie M. A., Lenders, Marie-Hélène, Gijbels, Marion J. J., Verheyen, Fons, Lütjohann, Dieter, Hofker, Marten H., Binder, Christoph J., Shiri-Sverdlov, Ronit
Publicado no Sci Rep (2017)

Co-expressed immune and metabolic genes in visceral and subcutaneous adipose tissue from severely obese individuals are associated with plasma HDL and glucose levels: a microarray...

Por Wolfs, Marcel GM, Rensen, Sander S, Bruin-Van Dijk, Elinda J, Verdam, Froukje J, Greve, Jan-Willem, Sanjabi, Bahram, Bruinenberg, Marcel, Wijmenga, Cisca, van Haeften, Timon W, Buurman, Wim A, Franke, Lude, Hofker, Marten H
Publicado em 2010

A cell-type-specific role for murine Commd1 in liver inflammation

Por Bartuzi, Paulina, Wijshake, Tobias, Dekker, Daphne C., Fedoseienko, Alina, Kloosterhuis, Niels J., Youssef, Sameh A., Li, Haiying, Shiri-Sverdlov, Ronit, Kuivenhoven, Jan-Albert, de Bruin, Alain, Burstein, Ezra, Hofker, Marten H., van de Sluis, Bart
Publicado em 2014

Effects of Anthocyanin and Flavanol Compounds on Lipid Metabolism and Adipose Tissue Associated Systemic Inflammation in Diet-Induced Obesity

Por van der Heijden, Roel A., Morrison, Martine C., Sheedfar, Fareeba, Mulder, Petra, Schreurs, Marijke, Hommelberg, Pascal P. H., Hofker, Marten H., Schalkwijk, Casper, Kleemann, Robert, Tietge, Uwe J. F., Koonen, Debby P. Y., Heeringa, Peter
Publicado no Mediators Inflamm (2016)

Role of Scavenger Receptor A and CD36 in Diet-Induced Nonalcoholic Steatohepatitis in Hyperlipidemic Mice

Por BIEGHS, VEERLE, WOUTERS, KRISTIAAN, VAN GORP, PATRICK J., GIJBELS, MARION J. J., DE WINTHER, MENNO P. J., BINDER, CHRISTOPH J., LÜTJOHANN, DIETER, FEBBRAIO, MARIA, MOORE, KATHRYN J., VAN BILSEN, MARC, HOFKER, MARTEN H., SHIRI–SVERDLOV, RONIT
Publicado em 2010

Chemokine-Like Receptor 1 Deficiency Does Not Affect the Development of Insulin Resistance and Nonalcoholic Fatty Liver Disease in Mice

Por Gruben, Nanda, Aparicio Vergara, Marcela, Kloosterhuis, Niels J., van der Molen, Henk, Stoelwinder, Stefan, Youssef, Sameh, de Bruin, Alain, Delsing, Dianne J., Kuivenhoven, Jan Albert, van de Sluis, Bart, Hofker, Marten H., Koonen, Debby P. Y.
Publicado em 2014