The HDL hypothesis: does high-density lipoprotein protect from atherosclerosis?

Por Vergeer, Menno, Holleboom, Adriaan G., Kastelein, John J. P., Kuivenhoven, Jan Albert
Publicado em 2010

LCAT synthesized by primary astrocytes esterifies cholesterol on glia-derived lipoproteins

Por Hirsch-Reinshagen, Veronica, Donkin, James, Stukas, Sophie, Chan, Jennifer, Wilkinson, Anna, Fan, Jianjia, Parks, John S., Kuivenhoven, Jan Albert, Lütjohann, Dieter, Pritchard, Haydn, Wellington, Cheryl L.
Publicado em 2009

eNOS Activation by HDL Is Impaired in Genetic CETP Deficiency

Por Gomaraschi, Monica, Ossoli, Alice, Pozzi, Silvia, Nilsson, Peter, Cefalù, Angelo B., Averna, Maurizio, Kuivenhoven, Jan Albert, Hovingh, G. Kees, Veglia, Fabrizio, Franceschini, Guido, Calabresi, Laura
Publicado em 2014

Hypercholesterolemia and reduced HDL-C promote hematopoietic stem cell proliferation and monocytosis: studies in mice and FH children

Por Tolani, Sonia, Pagler, Tamara A., Murphy, Andrew J., Bochem, Andrea E., Abramowicz, Sandra, Welch, Carrie, Nagareddy, Prabhakara R., Holleran, Steve, Hovingh, G.K., Kuivenhoven, Jan Albert, Tall, Alan R.
Publicado em 2013

LCAT deficiency in mice is associated with a diminished adrenal glucocorticoid function

Por Hoekstra, Menno, Korporaal, Suzanne J. A., van der Sluis, Ronald J., Hirsch-Reinshagen, Veronica, Bochem, Andrea E., Wellington, Cheryl L., Van Berkel, Theo J. C., Kuivenhoven, Jan Albert, Van Eck, Miranda
Publicado em 2013

Cholesterol-Induced Hepatic Inflammation Does Not Underlie the Predisposition to Insulin Resistance in Dyslipidemic Female LDL Receptor Knockout Mice

Por Gruben, Nanda, Funke, Anouk, Kloosterhuis, Niels J., Schreurs, Marijke, Sheedfar, Fareeba, Havinga, Rick, Houten, Sander M., Shiri-Sverdlov, Ronit, van de Sluis, Bart, Kuivenhoven, Jan Albert, Koonen, Debby P. Y., Hofker, Marten H.
Publicado no J Diabetes Res (2015)

ApoE regulates hematopoietic stem cell proliferation, monocytosis, and monocyte accumulation in atherosclerotic lesions in mice

Por Murphy, Andrew J., Akhtari, Mani, Tolani, Sonia, Pagler, Tamara, Bijl, Nora, Kuo, Chao-Ling, Wang, Mi, Sanson, Marie, Abramowicz, Sandra, Welch, Carrie, Bochem, Andrea E., Kuivenhoven, Jan Albert, Yvan-Charvet, Laurent, Tall, Alan R.
Publicado em 2011

A cell-type-specific role for murine Commd1 in liver inflammation

Por Bartuzi, Paulina, Wijshake, Tobias, Dekker, Daphne C., Fedoseienko, Alina, Kloosterhuis, Niels J., Youssef, Sameh A., Li, Haiying, Shiri-Sverdlov, Ronit, Kuivenhoven, Jan-Albert, de Bruin, Alain, Burstein, Ezra, Hofker, Marten H., van de Sluis, Bart
Publicado em 2014

Chemokine-Like Receptor 1 Deficiency Does Not Affect the Development of Insulin Resistance and Nonalcoholic Fatty Liver Disease in Mice

Por Gruben, Nanda, Aparicio Vergara, Marcela, Kloosterhuis, Niels J., van der Molen, Henk, Stoelwinder, Stefan, Youssef, Sameh, de Bruin, Alain, Delsing, Dianne J., Kuivenhoven, Jan Albert, van de Sluis, Bart, Hofker, Marten H., Koonen, Debby P. Y.
Publicado em 2014

Lipid Oxidation in Carriers of Lecithin:Cholesterol Acyltransferase Gene Mutations

Por Holleboom, Adriaan G., Daniil, Georgios, Fu, Xiaoming, Zhang, Renliang, Hovingh, G. Kees, Schimmel, Alinda W., Kastelein, John J.P., Stroes, Erik S.G., Witztum, Joseph L., Hutten, Barbara A., Tsimikas, Sotirios, Hazen, Stanley L., Chroni, Angeliki, Kuivenhoven, Jan Albert
Publicado em 2012

In vivo tissue cholesterol efflux is reduced in carriers of a mutation in APOA1

Por Holleboom, Adriaan G., Jakulj, Lily, Franssen, Remco, Decaris, Julie, Vergeer, Menno, Koetsveld, Joris, Luchoomun, Jayraz, Glass, Alexander, Hellerstein, Marc K., Kastelein, John J. P., Hovingh, G. Kees, Kuivenhoven, Jan Albert, Groen, Albert K., Turner, Scott M., Stroes, Erik S. G.
Publicado em 2013

Lipoprotein(a) as a cardiovascular risk factor: current status

Por Nordestgaard, Børge G., Chapman, M. John, Ray, Kausik, Borén, Jan, Andreotti, Felicita, Watts, Gerald F., Ginsberg, Henry, Amarenco, Pierre, Catapano, Alberico, Descamps, Olivier S., Fisher, Edward, Kovanen, Petri T., Kuivenhoven, Jan Albert, Lesnik, Philippe, Masana, Luis, Reiner, Zeljko, Taskinen, Marja-Riitta, Tokgözoglu, Lale, Tybjærg-Hansen, Anne
Publicado em 2010

Triglyceride-rich lipoproteins and high-density lipoprotein cholesterol in patients at high risk of cardiovascular disease: evidence and guidance for management

Por Chapman, M. John, Ginsberg, Henry N., Amarenco, Pierre, Andreotti, Felicita, Borén, Jan, Catapano, Alberico L., Descamps, Olivier S., Fisher, Edward, Kovanen, Petri T., Kuivenhoven, Jan Albert, Lesnik, Philippe, Masana, Luis, Nordestgaard, Børge G., Ray, Kausik K., Reiner, Zeljko, Taskinen, Marja-Riitta, Tokgözoglu, Lale, Tybjærg-Hansen, Anne, Watts, Gerald F.
Publicado em 2011

CCC- and WASH-mediated endosomal sorting of LDLR is required for normal clearance of circulating LDL

Por Bartuzi, Paulina, Billadeau, Daniel D., Favier, Robert, Rong, Shunxing, Dekker, Daphne, Fedoseienko, Alina, Fieten, Hille, Wijers, Melinde, Levels, Johannes H., Huijkman, Nicolette, Kloosterhuis, Niels, van der Molen, Henk, Brufau, Gemma, Groen, Albert K., Elliott, Alison M., Kuivenhoven, Jan Albert, Plecko, Barbara, Grangl, Gernot, McGaughran, Julie, Horton, Jay D., Burstein, Ezra, Hofker, Marten H., van de Sluis, Bart
Publicado no Nat Commun (2016)

The polygenic nature of hypertriglyceridaemia: implications for definition, diagnosis, and management

Por Hegele, Robert A, Ginsberg, Henry N, Chapman, M John, Nordestgaard, Børge G, Kuivenhoven, Jan Albert, Averna, Maurizio, Borén, Jan, Bruckert, Eric, Catapano, Alberico L, Descamps, Olivier S, Hovingh, G Kees, Humphries, Steve E, Kovanen, Petri T, Masana, Luis, Pajukanta, Päivi, Parhofer, Klaus G, Raal, Frederick J, Ray, Kausik K, Santos, Raul D, Stalenhoef, Anton F H, Stroes, Erik, Taskinen, Marja-Riitta, Tybjærg-Hansen, Anne, Watts, Gerald F, Wiklund, Olov
Publicado em 2013

Heterozygosity for a Loss-of-Function Mutation in GALNT2 Improves Plasma Triglyceride Clearance in Man

Por Holleboom, Adriaan G., Karlsson, Helen, Lin, Ruei-Shiuan, Beres, Thomas M., Sierts, Jeroen A., Herman, Daniel S., Stroes, Erik S.G., Aerts, Johannes M., Kastelein, John J.P., Motazacker, Mohammad M., Dallinga-Thie, Geesje M., Levels, Johannes H.M., Zwinderman, Aeilko H., Seidman, Jonathan G., Seidman, Christine E., Ljunggren, Stefan, Lefeber, Dirk J., Morava, Eva, Wevers, Ron A., Fritz, Timothy A., Tabak, Lawrence A., Lindahl, Mats, Hovingh, G. Kees, Kuivenhoven, Jan Albert
Publicado em 2011

Familial hypercholesterolaemia is underdiagnosed and undertreated in the general population: guidance for clinicians to prevent coronary heart disease: Consensus Statement of the E...

Por Nordestgaard, Børge G., Chapman, M. John, Humphries, Steve E., Ginsberg, Henry N., Masana, Luis, Descamps, Olivier S., Wiklund, Olov, Hegele, Robert A., Raal, Frederick J., Defesche, Joep C., Wiegman, Albert, Santos, Raul D., Watts, Gerald F., Parhofer, Klaus G., Hovingh, G. Kees, Kovanen, Petri T., Boileau, Catherine, Averna, Maurizio, Borén, Jan, Bruckert, Eric, Catapano, Alberico L., Kuivenhoven, Jan Albert, Pajukanta, Päivi, Ray, Kausik, Stalenhoef, Anton F. H., Stroes, Erik, Taskinen, Marja-Riitta, Tybjærg-Hansen, Anne
Publicado em 2013

Homozygous familial hypercholesterolaemia: new insights and guidance for clinicians to improve detection and clinical management. A position paper from the Consensus Panel on Famil...

Por Cuchel, Marina, Bruckert, Eric, Ginsberg, Henry N., Raal, Frederick J., Santos, Raul D., Hegele, Robert A., Kuivenhoven, Jan Albert, Nordestgaard, Børge G., Descamps, Olivier S., Steinhagen-Thiessen, Elisabeth, Tybjærg-Hansen, Anne, Watts, Gerald F., Averna, Maurizio, Boileau, Catherine, Borén, Jan, Catapano, Alberico L., Defesche, Joep C., Hovingh, G. Kees, Humphries, Steve E., Kovanen, Petri T., Masana, Luis, Pajukanta, Päivi, Parhofer, Klaus G., Ray, Kausik K., Stalenhoef, Anton F. H., Stroes, Erik, Taskinen, Marja-Riitta, Wiegman, Albert, Wiklund, Olov, Chapman, M. John, Cuchel, Marina, Bruckert, Eric, Chapman, M. John, Descamps, Olivier S., Ginsberg, Henry N., Hegele, Robert A., Kuivenhoven, Jan Albert, Nordestgaard, Børge G., Raal, Frederick J., Santos, Raul D., Steinhagen-Thiessen, Elisabeth, Tybjærg-Hansen, Anne, Watts, Gerald F., Chapman, M. John, Ginsberg, Henry N., Averna, Maurizio, Boileau, Catherine, Borén, Jan, Catapano, Alberico L., Defesche, Joep C., Hovingh, G. Kees, Humphries, Steve E., Kovanen, Petri T., Masana, Luis, Pajukanta, Päivi, Parhofer, Klaus G., Ray, Kausik K., Stalenhoef, Anton F. H., Stroes, Erik, Taskinen, Marja-Riitta, Wiegman, Albert, Wiklund, Olov
Publicado em 2014

Familial hypercholesterolaemia in children and adolescents: gaining decades of life by optimizing detection and treatment

Por Wiegman, Albert, Gidding, Samuel S., Watts, Gerald F., Chapman, M. John, Ginsberg, Henry N., Cuchel, Marina, Ose, Leiv, Averna, Maurizio, Boileau, Catherine, Borén, Jan, Bruckert, Eric, Catapano, Alberico L., Defesche, Joep C., Descamps, Olivier S., Hegele, Robert A., Hovingh, G. Kees, Humphries, Steve E., Kovanen, Petri T., Kuivenhoven, Jan Albert, Masana, Luis, Nordestgaard, Børge G., Pajukanta, Päivi, Parhofer, Klaus G., Raal, Frederick J., Ray, Kausik K., Santos, Raul D., Stalenhoef, Anton F.H., Steinhagen- Thiessen, Elisabeth, Stroes, Erik S., Taskinen, Marja-Riitta, Tybjærg-Hansen, Anne, Wiklund, Olov
Publicado no Eur Heart J (2015)