eNOS Activation by HDL Is Impaired in Genetic CETP Deficiency

Mutations in the CETP gene resulting in defective CETP activity have been shown to cause remarkable elevations of plasma HDL-C levels, with the accumulation in plasma of large, buoyant HDL particles enriched in apolipoprotein E. Genetic CETP deficiency thus represents a unique tool to evaluate how s...

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Main Authors: Gomaraschi, Monica, Ossoli, Alice, Pozzi, Silvia, Nilsson, Peter, Cefalù, Angelo B., Averna, Maurizio, Kuivenhoven, Jan Albert, Hovingh, G. Kees, Veglia, Fabrizio, Franceschini, Guido, Calabresi, Laura
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4022511/
https://ncbi.nlm.nih.gov/pubmed/24830642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0095925
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