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ApoE regulates hematopoietic stem cell proliferation, monocytosis, and monocyte accumulation in atherosclerotic lesions in mice

Leukocytosis is associated with increased cardiovascular disease risk in humans and develops in hypercholesterolemic atherosclerotic animal models. Leukocytosis is associated with the proliferation of hematopoietic stem and multipotential progenitor cells (HSPCs) in mice with deficiencies of the cho...

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Bibliografiska uppgifter
Huvudupphovsmän: Murphy, Andrew J., Akhtari, Mani, Tolani, Sonia, Pagler, Tamara, Bijl, Nora, Kuo, Chao-Ling, Wang, Mi, Sanson, Marie, Abramowicz, Sandra, Welch, Carrie, Bochem, Andrea E., Kuivenhoven, Jan Albert, Yvan-Charvet, Laurent, Tall, Alan R.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Clinical Investigation 2011
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3195472/
https://ncbi.nlm.nih.gov/pubmed/21968112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI57559
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