ApoE regulates hematopoietic stem cell proliferation, monocytosis, and monocyte accumulation in atherosclerotic lesions in mice

Leukocytosis is associated with increased cardiovascular disease risk in humans and develops in hypercholesterolemic atherosclerotic animal models. Leukocytosis is associated with the proliferation of hematopoietic stem and multipotential progenitor cells (HSPCs) in mice with deficiencies of the cho...

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Detalhes bibliográficos
Main Authors: Murphy, Andrew J., Akhtari, Mani, Tolani, Sonia, Pagler, Tamara, Bijl, Nora, Kuo, Chao-Ling, Wang, Mi, Sanson, Marie, Abramowicz, Sandra, Welch, Carrie, Bochem, Andrea E., Kuivenhoven, Jan Albert, Yvan-Charvet, Laurent, Tall, Alan R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3195472/
https://ncbi.nlm.nih.gov/pubmed/21968112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI57559
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