ApoE regulates hematopoietic stem cell proliferation, monocytosis, and monocyte accumulation in atherosclerotic lesions in mice

Leukocytosis is associated with increased cardiovascular disease risk in humans and develops in hypercholesterolemic atherosclerotic animal models. Leukocytosis is associated with the proliferation of hematopoietic stem and multipotential progenitor cells (HSPCs) in mice with deficiencies of the cho...

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Autores principales: Murphy, Andrew J., Akhtari, Mani, Tolani, Sonia, Pagler, Tamara, Bijl, Nora, Kuo, Chao-Ling, Wang, Mi, Sanson, Marie, Abramowicz, Sandra, Welch, Carrie, Bochem, Andrea E., Kuivenhoven, Jan Albert, Yvan-Charvet, Laurent, Tall, Alan R.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2011
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3195472/
https://ncbi.nlm.nih.gov/pubmed/21968112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI57559
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