ApoE regulates hematopoietic stem cell proliferation, monocytosis, and monocyte accumulation in atherosclerotic lesions in mice

Leukocytosis is associated with increased cardiovascular disease risk in humans and develops in hypercholesterolemic atherosclerotic animal models. Leukocytosis is associated with the proliferation of hematopoietic stem and multipotential progenitor cells (HSPCs) in mice with deficiencies of the cho...

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Autori principali: Murphy, Andrew J., Akhtari, Mani, Tolani, Sonia, Pagler, Tamara, Bijl, Nora, Kuo, Chao-Ling, Wang, Mi, Sanson, Marie, Abramowicz, Sandra, Welch, Carrie, Bochem, Andrea E., Kuivenhoven, Jan Albert, Yvan-Charvet, Laurent, Tall, Alan R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2011
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3195472/
https://ncbi.nlm.nih.gov/pubmed/21968112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI57559
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