Cholesterol-Induced Hepatic Inflammation Does Not Underlie the Predisposition to Insulin Resistance in Dyslipidemic Female LDL Receptor Knockout Mice

Chronic inflammation is considered a causal risk factor predisposing to insulin resistance. However, evidence is accumulating that inflammation confined to the liver may not be causal to metabolic dysfunction. To investigate this, we assessed if hepatic inflammation explains the predisposition towar...

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Bibliographic Details
Published in:J Diabetes Res
Main Authors: Gruben, Nanda, Funke, Anouk, Kloosterhuis, Niels J., Schreurs, Marijke, Sheedfar, Fareeba, Havinga, Rick, Houten, Sander M., Shiri-Sverdlov, Ronit, van de Sluis, Bart, Kuivenhoven, Jan Albert, Koonen, Debby P. Y., Hofker, Marten H.
Format: Artigo
Language:Inglês
Published: Hindawi Publishing Corporation 2015
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4359820/
https://ncbi.nlm.nih.gov/pubmed/25815343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/956854
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