Hematopoietic Npc1 mutation shifts gut microbiota composition in Ldlr(−/−) mice on a high-fat, high-cholesterol diet

While the link between diet-induced changes in gut microbiota and lipid metabolism in metabolic syndrome (MetS) has been established, the contribution of host genetics is rather unexplored. As several findings suggested a role for the lysosomal lipid transporter Niemann-Pick type C1 (NPC1) in macrop...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Houben, Tom, Penders, John, Oligschlaeger, Yvonne, dos Reis, Inês A. Magro, Bonder, Marc-Jan, Koonen, Debby P., Fu, Jingyuan, Hofker, Marten H., Shiri-Sverdlov, Ronit
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6802207/
https://ncbi.nlm.nih.gov/pubmed/31628414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-51525-x
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