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5-aminosalicylic acid improves lipid profile in mice fed a high-fat cholesterol diet through its dual effects on intestinal PPARγ and PPARα

Obesity is associated with a series of metabolic complications, including dyslipidemia and insulin resistance (IR) that lack effective therapies. In recent years, intestinal inflammation has been suggested to contribute to obesity related metabolic syndrome and targeting gut inflammation with 5-ASA...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Wang, Zheng, Koonen, Debby, Hofker, Marten, Bao, Zhijun
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5774772/
https://ncbi.nlm.nih.gov/pubmed/29352300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0191485
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