The 5-aminosalicylic acid antineoplastic effect in the intestine is mediated by PPARγ

Epidemiological evidences suggested that 5-aminosalicylic acid (5-ASA) therapy may prevent the development of colorectal cancer in inflammatory bowel disease patients. Our aim is to investigate whether peroxisome proliferator-activated receptor-γ (PPARγ) mediates the antineoplastic effects of 5-ASA....

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Detalhes bibliográficos
Main Authors: Rousseaux, Christel, El-Jamal, Noura, Fumery, Mathurin, Dubuquoy, Caroline, Romano, Olivier, Chatelain, Denis, Langlois, Audrey, Bertin, Benjamin, Buob, David, Colombel, Jean Frederic, Cortot, Antoine, Desreumaux, Pierre, Dubuquoy, Laurent
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
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Original Manuscript
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3810841/
https://ncbi.nlm.nih.gov/pubmed/23843037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgt245
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