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Intestinal antiinflammatory effect of 5-aminosalicylic acid is dependent on peroxisome proliferator–activated receptor-γ

5-aminosalicylic acid (5-ASA) is an antiinflammatory drug widely used in the treatment of inflammatory bowel diseases. It is known to inhibit the production of cytokines and inflammatory mediators, but the mechanism underlying the intestinal effects of 5-ASA remains unknown. Based on the common acti...

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Detalhes bibliográficos
Main Authors: Rousseaux, Christel, Lefebvre, Bruno, Dubuquoy, Laurent, Lefebvre, Philippe, Romano, Olivier, Auwerx, Johan, Metzger, Daniel, Wahli, Walter, Desvergne, Béatrice, Naccari, Gian Carlo, Chavatte, Philippe, Farce, Amaury, Bulois, Philippe, Cortot, Antoine, Colombel, Jean Frédéric, Desreumaux, Pierre
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2213148/
https://ncbi.nlm.nih.gov/pubmed/15824083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20041948
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