Intestinal antiinflammatory effect of 5-aminosalicylic acid is dependent on peroxisome proliferator–activated receptor-γ

5-aminosalicylic acid (5-ASA) is an antiinflammatory drug widely used in the treatment of inflammatory bowel diseases. It is known to inhibit the production of cytokines and inflammatory mediators, but the mechanism underlying the intestinal effects of 5-ASA remains unknown. Based on the common acti...

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Hlavní autoři: Rousseaux, Christel, Lefebvre, Bruno, Dubuquoy, Laurent, Lefebvre, Philippe, Romano, Olivier, Auwerx, Johan, Metzger, Daniel, Wahli, Walter, Desvergne, Béatrice, Naccari, Gian Carlo, Chavatte, Philippe, Farce, Amaury, Bulois, Philippe, Cortot, Antoine, Colombel, Jean Frédéric, Desreumaux, Pierre
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2005
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2213148/
https://ncbi.nlm.nih.gov/pubmed/15824083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20041948
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