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5-aminosalicylic acid improves lipid profile in mice fed a high-fat cholesterol diet through its dual effects on intestinal PPARγ and PPARα

Obesity is associated with a series of metabolic complications, including dyslipidemia and insulin resistance (IR) that lack effective therapies. In recent years, intestinal inflammation has been suggested to contribute to obesity related metabolic syndrome and targeting gut inflammation with 5-ASA...

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Bibliographic Details
Published in:PLoS One
Main Authors: Wang, Zheng, Koonen, Debby, Hofker, Marten, Bao, Zhijun
Format: Artigo
Language:Inglês
Published: Public Library of Science 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5774772/
https://ncbi.nlm.nih.gov/pubmed/29352300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0191485
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