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SAT-152 Loss of Hepatocyte PPARγ Expression Ameliorates Steatosis in Mice Fed a High-Fat, Cholesterol, and Fructose Diet, but Not in Mice Fed a Methionine- and Choline-Deficient Diet
Hepatic PPARγ expression is positively associated with the progression of non-alcoholic fatty liver disease and non-alcoholic steatohepatitis (NASH) in mice and humans. Although PPARγ agonists, thiazolidinediones (TZD), could be used to treat patients with NASH, these drugs reduced steatosis only in...
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| Publicado no: | J Endocr Soc |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Endocrine Society
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6552036/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/js.2019-SAT-152 |
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