The polygenic nature of hypertriglyceridaemia: implications for definition, diagnosis, and management

Plasma triglyceride concentration is a biomarker for circulating triglyceride-rich lipoproteins and their metabolic remnants. Common mild-to-moderate hypertriglyceridaemia is typically multigenic, and results from the cumulative burden of common and rare variants in more than 30 genes, as quantified...

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Detalhes bibliográficos
Main Authors: Hegele, Robert A, Ginsberg, Henry N, Chapman, M John, Nordestgaard, Børge G, Kuivenhoven, Jan Albert, Averna, Maurizio, Borén, Jan, Bruckert, Eric, Catapano, Alberico L, Descamps, Olivier S, Hovingh, G Kees, Humphries, Steve E, Kovanen, Petri T, Masana, Luis, Pajukanta, Päivi, Parhofer, Klaus G, Raal, Frederick J, Ray, Kausik K, Santos, Raul D, Stalenhoef, Anton F H, Stroes, Erik, Taskinen, Marja-Riitta, Tybjærg-Hansen, Anne, Watts, Gerald F, Wiklund, Olov
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4201123/
https://ncbi.nlm.nih.gov/pubmed/24731657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S2213-8587(13)70191-8
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