Development of Antibody‐Directed Therapies: Quo Vadis?

Por Rodrigues, Tiago, Bernardes, Gonçalo J. L.
Publicado no Angew Chem Int Ed Engl (2018)

Trends in therapeutic drug conjugates for bacterial diseases: a patent review

Por Cal, Pedro M. S. D., Matos, Maria J., Bernardes, Gonçalo J. L.
Publicado no Expert Opin Ther Pat (2016)

Radical‐Mediated Thiol‐Ene Strategy: Photoactivation of Thiol‐Containing Drugs in Cancer Cells

Por Sun, Shuang, Oliveira, Bruno L., Jiménez‐Osés, Gonzalo, Bernardes, Gonçalo J. L.
Publicado no Angew Chem Int Ed Engl (2018)

Synthetically defined glycoprotein vaccines: current status and future directions

Por Adamo, Roberto, Nilo, Alberto, Castagner, Bastien, Boutureira, Omar, Berti, Francesco, Bernardes, Gonçalo J. L.
Publicado no Chem Sci (2013)

A thioether-directed palladium-cleavable linker for targeted bioorthogonal drug decaging

Por Stenton, Benjamin J., Oliveira, Bruno L., Matos, Maria J., Sinatra, Laura, Bernardes, Gonçalo J. L.
Publicado no Chem Sci (2018)

Modular Pore-Forming Immunotoxins with Caged Cytotoxicity Tailored by Directed Evolution

Por Mutter, Natalie L., Soskine, Misha, Huang, Gang, Albuquerque, Inês S., Bernardes, Gonçalo J. L., Maglia, Giovanni
Publicado no ACS Chem Biol (2018)

A Minimal, Unstrained S‐Allyl Handle for Pre‐Targeting Diels–Alder Bioorthogonal Labeling in Live Cells

Por Oliveira, Bruno L., Guo, Zijian, Boutureira, Omar, Guerreiro, Ana, Jiménez‐Osés, Gonzalo, Bernardes, Gonçalo J. L.
Publicado no Angew Chem Int Ed Engl (2016)

Synthesis and Biological Evaluation of Homogeneous Thiol‐Linked NHC*‐Au‐Albumin and ‐Trastuzumab Bioconjugates

Por Matos, Maria J., Labão‐Almeida, Carlos, Sayers, Claire, Dada, Oyinlola, Tacke, Matthias, Bernardes, Gonçalo J. L.
Publicado no Chemistry (2018)

Site‐Selective Modification of Proteins with Oxetanes

Por Boutureira, Omar, Martínez‐Sáez, Nuria, Brindle, Kevin M., Neves, André A., Corzana, Francisco, Bernardes, Gonçalo J. L.
Publicado no Chemistry (2017)

Iminoboronates are efficient intermediates for selective, rapid and reversible N-terminal cysteine functionalisation

Por Faustino, Hélio, Silva, Maria J. S. A., Veiros, Luís F., Bernardes, Gonçalo J. L., Gois, Pedro M. P.
Publicado no Chem Sci (2016)

Correction: Iminoboronates are efficient intermediates for selective, rapid and reversible N-terminal cysteine functionalisation

Por Faustino, Hélio, Silva, Maria J. S. A., Veiros, Luís F., Bernardes, Gonçalo J. L., Gois, Pedro M. P.
Publicado no Chem Sci (2016)

Enhanced Permeability and Binding Activity of Isobutylene‐Grafted Peptides

Por Sun, Shuang, Compañón, Ismael, Martínez‐Sáez, Nuria, Seixas, João D., Boutureira, Omar, Corzana, Francisco, Bernardes, Gonçalo J. L.
Publicado no Chembiochem (2017)

Unveiling (−)‐Englerin A as a Modulator of L‐Type Calcium Channels

Por Rodrigues, Tiago, Sieglitz, Florian, Somovilla, Víctor J., Cal, Pedro M. S. D., Galione, Antony, Corzana, Francisco, Bernardes, Gonçalo J. L.
Publicado no Angew Chem Int Ed Engl (2016)

Construction of homogeneous antibody–drug conjugates using site-selective protein chemistry

Por Akkapeddi, Padma, Azizi, Saara-Anne, Freedy, Allyson M., Cal, Pedro M. S. D., Gois, Pedro M. P., Bernardes, Gonçalo J. L.
Publicado no Chem Sci (2016)

Spontaneous CO Release from Ru(II)(CO)(2)–Protein Complexes in Aqueous Solution, Cells, and Mice**

Por Chaves-Ferreira, Miguel, Albuquerque, Inês S, Matak-Vinkovic, Dijana, Coelho, Ana C, Carvalho, Sandra M, Saraiva, Lígia M, Romão, Carlos C, Bernardes, Gonçalo J L
Publicado no Angew Chem Int Ed Engl (2015)

Precise Probing of Residue Roles by Post-Translational β,γ-C,N Aza-Michael Mutagenesis in Enzyme Active Sites

Por Dadová, Jitka, Wu, Kuan-Jung, Isenegger, Patrick G., Errey, James C., Bernardes, Gonçalo J. L., Chalker, Justin M., Raich, Lluís, Rovira, Carme, Davis, Benjamin G.
Publicado no ACS Cent Sci (2017)

Vinyl Ether/Tetrazine Pair for the Traceless Release of Alcohols in Cells

Por Jiménez‐Moreno, Ester, Guo, Zijian, Oliveira, Bruno L., Albuquerque, Inês S., Kitowski, Annabel, Guerreiro, Ana, Boutureira, Omar, Rodrigues, Tiago, Jiménez‐Osés, Gonzalo, Bernardes, Gonçalo J. L.
Publicado no Angew Chem Int Ed Engl (2016)

A Novel Carbon Monoxide-Releasing Molecule Fully Protects Mice from Severe Malaria

Por Pena, Ana C., Penacho, Nuno, Mancio-Silva, Liliana, Neres, Rita, Seixas, João D., Fernandes, Afonso C., Romão, Carlos C., Mota, Maria M., Bernardes, Gonçalo J. L., Pamplona, Ana
Publicado em 2012

An N-Acetyl Cysteine Ruthenium Tricarbonyl Conjugate Enables Simultaneous Release of CO and Ablation of Reactive Oxygen Species

Por Seixas, João D, Chaves-Ferreira, Miguel, Montes-Grajales, Diana, Gonçalves, Ana M, Marques, Ana R, Saraiva, Lígia M, Olivero-Verbel, Jesus, Romão, Carlos C, Bernardes, Gonçalo J L
Publicado no Chemistry (2015)

Oxetane Grafts Installed Site‐Selectively on Native Disulfides to Enhance Protein Stability and Activity In Vivo

Por Martínez‐Sáez, Nuria, Sun, Shuang, Oldrini, Davide, Sormanni, Pietro, Boutureira, Omar, Carboni, Filippo, Compañón, Ismael, Deery, Michael J., Vendruscolo, Michele, Corzana, Francisco, Adamo, Roberto, Bernardes, Gonçalo J. L.
Publicado no Angew Chem Int Ed Engl (2017)