Vinyl Ether/Tetrazine Pair for the Traceless Release of Alcohols in Cells

The cleavage of a protecting group from a protein or drug under bioorthogonal conditions enables accurate spatiotemporal control over protein or drug activity. Disclosed herein is that vinyl ethers serve as protecting groups for alcohol‐containing molecules and as reagents for bioorthogonal bond‐cle...

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發表在:Angew Chem Int Ed Engl
Main Authors: Jiménez‐Moreno, Ester, Guo, Zijian, Oliveira, Bruno L., Albuquerque, Inês S., Kitowski, Annabel, Guerreiro, Ana, Boutureira, Omar, Rodrigues, Tiago, Jiménez‐Osés, Gonzalo, Bernardes, Gonçalo J. L.
格式: Artigo
語言:Inglês
出版: John Wiley and Sons Inc. 2016
主題:
Communications
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6485351/
https://ncbi.nlm.nih.gov/pubmed/27930843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201609607
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