Vinyl Ether/Tetrazine Pair for the Traceless Release of Alcohols in Cells

The cleavage of a protecting group from a protein or drug under bioorthogonal conditions enables accurate spatiotemporal control over protein or drug activity. Disclosed herein is that vinyl ethers serve as protecting groups for alcohol‐containing molecules and as reagents for bioorthogonal bond‐cle...

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Vydáno v:Angew Chem Int Ed Engl
Hlavní autoři: Jiménez‐Moreno, Ester, Guo, Zijian, Oliveira, Bruno L., Albuquerque, Inês S., Kitowski, Annabel, Guerreiro, Ana, Boutureira, Omar, Rodrigues, Tiago, Jiménez‐Osés, Gonzalo, Bernardes, Gonçalo J. L.
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2016
Témata:
Communications
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6485351/
https://ncbi.nlm.nih.gov/pubmed/27930843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201609607
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