A carregar...
A thioether-directed palladium-cleavable linker for targeted bioorthogonal drug decaging
We describe the development of a bifunctional linker that simultaneously allows site-specific protein modification and palladium-mediated bioorthogonal decaging. This was enabled by a thioether binding motif in the propargyl carbamate linker and a readily available palladium complex. We demonstrate...
Na minha lista:
| Publicado no: | Chem Sci |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Royal Society of Chemistry
2018
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5941270/ https://ncbi.nlm.nih.gov/pubmed/29780549 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8sc00256h |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|