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Highly multiplexed single-cell in situ RNA and DNA analysis with bioorthogonal cleavable fluorescent oligonucleotides

The ability to profile transcripts and genomic loci comprehensively in single cells in situ is essential to advance our understanding of normal physiology and disease pathogenesis. Here we report a highly multiplexed single-cell in situ RNA and DNA analysis approach using bioorthogonal cleavable flu...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Mondal, Manas, Liao, Renjie, Nazaroff, Christopher D., Samuel, Adam D., Guo, Jia
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5914540/
https://ncbi.nlm.nih.gov/pubmed/29732074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7sc05089e
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