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Site‐Selective Modification of Proteins with Oxetanes
Oxetanes are four‐membered ring oxygen heterocycles that are advantageously used in medicinal chemistry as modulators of physicochemical properties of small molecules. Herein, we present a simple method for the incorporation of oxetanes into proteins through chemoselective alkylation of cysteine. We...
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| Publicat a: | Chemistry |
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| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
John Wiley and Sons Inc.
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5434895/ https://ncbi.nlm.nih.gov/pubmed/28261889 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201700745 |
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