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Site‐Selective Modification of Proteins with Oxetanes

Oxetanes are four‐membered ring oxygen heterocycles that are advantageously used in medicinal chemistry as modulators of physicochemical properties of small molecules. Herein, we present a simple method for the incorporation of oxetanes into proteins through chemoselective alkylation of cysteine. We...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Chemistry
Päätekijät: Boutureira, Omar, Martínez‐Sáez, Nuria, Brindle, Kevin M., Neves, André A., Corzana, Francisco, Bernardes, Gonçalo J. L.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley and Sons Inc. 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5434895/
https://ncbi.nlm.nih.gov/pubmed/28261889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201700745
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