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Radical‐Mediated Thiol‐Ene Strategy: Photoactivation of Thiol‐Containing Drugs in Cancer Cells
Photoactivated drugs provide an opportunity to improve efficacy alongside reducing side‐effects in the treatment of severe diseases such as cancer. Described herein is a photoactivation decaging method of isobutylene‐caged thiols through a UV‐initiated thiol‐ene reaction. The method was demonstrated...
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| Publicado no: | Angew Chem Int Ed Engl |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6391964/ https://ncbi.nlm.nih.gov/pubmed/30300959 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201811338 |
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