Hydrogen-Deuterium Exchange and Hydroxyl Radical Footprinting for Mapping Hydrophobic Interactions of Human Bromodomain with a Small Molecule Inhibitor

著者: Li, Ke Sherry, Bergman, Elizabeth, Beno, Brett R., Huang, Richard Y.-C., Deyanova, Ekaterina, Chen, Guodong, Gross, Michael L.
出版年 J Am Soc Mass Spectrom (2019)

Resistance profile of the HIV-1 maturation inhibitor GSK3532795 in vitro and in a clinical study

著者: Dicker, Ira, Zhang, Sharon, Ray, Neelanjana, Beno, Brett R., Regueiro-Ren, Alicia, Joshi, Samit, Cockett, Mark, Krystal, Mark, Lataillade, Max
出版年 PLoS One (2019)

Epitope and Paratope Mapping of PD-1/Nivolumab by Mass Spectrometry-based Hydrogen/Deuterium Exchange, Cross-linking, and Molecular Docking

著者: Zhang, Mengru Mira, Huang, Richard Y.-C., Beno, Brett R., Deyanova, Ekaterina G., Li, Jing, Chen, Guodong, Gross, Michael L.
出版年 Anal Chem (2020)

An Integrated Approach for Determining a Protein-Protein Binding Interface in Solution and an Evaluation of HDX Kinetics for Adjudicating Candidate Docking Models

著者: Zhang, Mengru Mira, Beno, Brett R., Huang, Richard Y.-C., Adhikari, Jagat, Deyanova, Ekaterina G., Li, Jing, Chen, Guodong, Gross, Michael L.
出版年 Anal Chem (2019)

Orthogonal Mass Spectrometry-Based Footprinting for Epitope Mapping and Structural Characterization: The IL-6 Receptor upon Binding of Protein Therapeutics

著者: Li, Ke Sherry, Chen, Guodong, Mo, Jingjie, Huang, Richard Y-C, Deyanova, Ekaterina G., Beno, Brett R., O’Neil, Steve R., Tymiak, Adrienne A., Gross, Michael L.
出版年 Anal Chem (2017)

A Small Molecule Inhibitor Selectively Induces Apoptosis in Cells Transformed by High Risk Human Papilloma Viruses

著者: Sheaffer, Amy K., Lee, Min S., Qi, Huilin, Chaniewski, Susan, Zheng, Xiaofan, Farr, Glen A., Esposito, Kim, Harden, David, Lei, Ming, Schweizer, Liang, Friborg, Jacques, Agler, Michele, McPhee, Fiona, Gentles, Robert, Beno, Brett R., Chupak, Lou, Mason, Stephen
出版年 PLoS One (2016)

High-Throughput Screening and Rapid Inhibitor Triage Using an Infectious Chimeric Hepatitis C Virus

著者: Wichroski, Michael J., Fang, Jie, Eggers, Betsy J., Rose, Ronald E., Mazzucco, Charles E., Pokornowski, Kevin A., Baldick, Carl J., Anthony, Monique N., Dowling, Craig J., Barber, Lauren E., Leet, John E., Beno, Brett R., Gerritz, Samuel W., Agler, Michele L., Cockett, Mark I., Tenney, Daniel J.
出版事項 2012

Discovery of BMS-955176, a Second Generation HIV-1 Maturation Inhibitor with Broad Spectrum Antiviral Activity

著者: Regueiro-Ren, Alicia, Liu, Zheng, Chen, Yan, Sin, Ny, Sit, Sing-Yuen, Swidorski, Jacob J., Chen, Jie, Venables, Brian L., Zhu, Juliang, Nowicka-Sans, Beata, Protack, Tricia, Lin, Zeyu, Terry, Brian, Samanta, Himadri, Zhang, Sharon, Li, Zhufang, Beno, Brett R., Huang, Xiaohua S., Rahematpura, Sandhya, Parker, Dawn D., Haskell, Roy, Jenkins, Susan, Santone, Kenneth S., Cockett, Mark I., Krystal, Mark, Meanwell, Nicholas A., Hanumegowda, Umesh, Dicker, Ira B.
出版年 ACS Med Chem Lett (2016)

Structure–Property Basis for Solving Transporter-Mediated Efflux and Pan-Genotypic Inhibition in HCV NS5B Inhibitors

著者: Yeung, Kap-Sun, Beno, Brett R., Mosure, Kathy, Zhu, Juliang, Grant-Young, Katherine A., Parcella, Kyle, Anjanappa, Prakash, Bora, Rajesh Onkardas, Selvakumar, Kumaravel, Wang, Ying-Kai, Fang, Hua, Krause, Rudolph, Rigat, Karen, Liu, Mengping, Lemm, Julie, Sheriff, Steven, Witmer, Mark, Tredup, Jeffrey, Jardel, Adam, Kish, Kevin, Parker, Dawn, Haskell, Roy, Santone, Kenneth, Meanwell, Nicholas A., Soars, Matthew G., Roberts, Susan B., Kadow, John F.
出版年 ACS Med Chem Lett (2018)

The discovery of a pan-genotypic, primer grip inhibitor of HCV NS5B polymerase

著者: Eastman, Kyle J., Parcella, Kyle, Yeung, Kap-Sun, Grant-Young, Katharine A., Zhu, Juliang, Wang, Tao, Zhang, Zhongxing, Yin, Zhiwei, Beno, Brett R., Sheriff, Steven, Kish, Kevin, Tredup, Jeffrey, Jardel, Adam G., Halan, Vivek, Ghosh, Kaushik, Parker, Dawn, Mosure, Kathy, Fang, Hua, Wang, Ying-Kai, Lemm, Julie, Zhuo, Xiaoliang, Hanumegowda, Umesh, Rigat, Karen, Donoso, Maria, Tuttle, Maria, Zvyaga, Tatyana, Haarhoff, Zuzana, Meanwell, Nicholas A., Soars, Matthew G., Roberts, Susan B., Kadow, John F.
出版年 Medchemcomm (2017)