Mathematical Models to Explore Potential Effects of Supersaturation and Precipitation on Oral Bioavailability of Poorly Soluble Drugs

Por Kleppe, Mary S., Forney-Stevens, Kelly M., Haskell, Roy J., Bogner, Robin H.
Publicado no AAPS J (2015)

Discovery of BMS-955176, a Second Generation HIV-1 Maturation Inhibitor with Broad Spectrum Antiviral Activity

Por Regueiro-Ren, Alicia, Liu, Zheng, Chen, Yan, Sin, Ny, Sit, Sing-Yuen, Swidorski, Jacob J., Chen, Jie, Venables, Brian L., Zhu, Juliang, Nowicka-Sans, Beata, Protack, Tricia, Lin, Zeyu, Terry, Brian, Samanta, Himadri, Zhang, Sharon, Li, Zhufang, Beno, Brett R., Huang, Xiaohua S., Rahematpura, Sandhya, Parker, Dawn D., Haskell, Roy, Jenkins, Susan, Santone, Kenneth S., Cockett, Mark I., Krystal, Mark, Meanwell, Nicholas A., Hanumegowda, Umesh, Dicker, Ira B.
Publicado no ACS Med Chem Lett (2016)

Design and Synthesis of 4-Heteroaryl 1,2,3,4-Tetrahydroisoquinolines as Triple Reuptake Inhibitors

Por Liu, Shuang, Zha, Congxiang, Nacro, Kassoum, Hu, Min, Cui, Wenge, Yang, Yuh-Lin, Bhatt, Ulhas, Sambandam, Aruna, Isherwood, Matthew, Yet, Larry, Herr, Michael T., Ebeltoft, Sarah, Hassler, Carla, Fleming, Linda, Pechulis, Anthony D., Payen-Fornicola, Anne, Holman, Nicholas, Milanowski, Dennis, Cotterill, Ian, Mozhaev, Vadim, Khmelnitsky, Yuri, Guzzo, Peter R., Sargent, Bruce J., Molino, Bruce F., Olson, Richard, King, Dalton, Lelas, Snjezana, Li, Yu-Wen, Johnson, Kim, Molski, Thaddeus, Orie, Anitra, Ng, Alicia, Haskell, Roy, Clarke, Wendy, Bertekap, Robert, O’Connell, Jonathan, Lodge, Nicholas, Sinz, Michael, Adams, Stephen, Zaczek, Robert, Macor, John E.
Publicado em 2014