Hydrogen-Deuterium Exchange and Hydroxyl Radical Footprinting for Mapping Hydrophobic Interactions of Human Bromodomain with a Small Molecule Inhibitor

Por Li, Ke Sherry, Bergman, Elizabeth, Beno, Brett R., Huang, Richard Y.-C., Deyanova, Ekaterina, Chen, Guodong, Gross, Michael L.
Publicado no J Am Soc Mass Spectrom (2019)

Resistance profile of the HIV-1 maturation inhibitor GSK3532795 in vitro and in a clinical study

Por Dicker, Ira, Zhang, Sharon, Ray, Neelanjana, Beno, Brett R., Regueiro-Ren, Alicia, Joshi, Samit, Cockett, Mark, Krystal, Mark, Lataillade, Max
Publicado no PLoS One (2019)

Epitope and Paratope Mapping of PD-1/Nivolumab by Mass Spectrometry-based Hydrogen/Deuterium Exchange, Cross-linking, and Molecular Docking

Por Zhang, Mengru Mira, Huang, Richard Y.-C., Beno, Brett R., Deyanova, Ekaterina G., Li, Jing, Chen, Guodong, Gross, Michael L.
Publicado no Anal Chem (2020)

An Integrated Approach for Determining a Protein-Protein Binding Interface in Solution and an Evaluation of HDX Kinetics for Adjudicating Candidate Docking Models

Por Zhang, Mengru Mira, Beno, Brett R., Huang, Richard Y.-C., Adhikari, Jagat, Deyanova, Ekaterina G., Li, Jing, Chen, Guodong, Gross, Michael L.
Publicado no Anal Chem (2019)

Orthogonal Mass Spectrometry-Based Footprinting for Epitope Mapping and Structural Characterization: The IL-6 Receptor upon Binding of Protein Therapeutics

Por Li, Ke Sherry, Chen, Guodong, Mo, Jingjie, Huang, Richard Y-C, Deyanova, Ekaterina G., Beno, Brett R., O’Neil, Steve R., Tymiak, Adrienne A., Gross, Michael L.
Publicado no Anal Chem (2017)

A Small Molecule Inhibitor Selectively Induces Apoptosis in Cells Transformed by High Risk Human Papilloma Viruses

Por Sheaffer, Amy K., Lee, Min S., Qi, Huilin, Chaniewski, Susan, Zheng, Xiaofan, Farr, Glen A., Esposito, Kim, Harden, David, Lei, Ming, Schweizer, Liang, Friborg, Jacques, Agler, Michele, McPhee, Fiona, Gentles, Robert, Beno, Brett R., Chupak, Lou, Mason, Stephen
Publicado no PLoS One (2016)

High-Throughput Screening and Rapid Inhibitor Triage Using an Infectious Chimeric Hepatitis C Virus

Por Wichroski, Michael J., Fang, Jie, Eggers, Betsy J., Rose, Ronald E., Mazzucco, Charles E., Pokornowski, Kevin A., Baldick, Carl J., Anthony, Monique N., Dowling, Craig J., Barber, Lauren E., Leet, John E., Beno, Brett R., Gerritz, Samuel W., Agler, Michele L., Cockett, Mark I., Tenney, Daniel J.
Publicado em 2012

Discovery of BMS-955176, a Second Generation HIV-1 Maturation Inhibitor with Broad Spectrum Antiviral Activity

Por Regueiro-Ren, Alicia, Liu, Zheng, Chen, Yan, Sin, Ny, Sit, Sing-Yuen, Swidorski, Jacob J., Chen, Jie, Venables, Brian L., Zhu, Juliang, Nowicka-Sans, Beata, Protack, Tricia, Lin, Zeyu, Terry, Brian, Samanta, Himadri, Zhang, Sharon, Li, Zhufang, Beno, Brett R., Huang, Xiaohua S., Rahematpura, Sandhya, Parker, Dawn D., Haskell, Roy, Jenkins, Susan, Santone, Kenneth S., Cockett, Mark I., Krystal, Mark, Meanwell, Nicholas A., Hanumegowda, Umesh, Dicker, Ira B.
Publicado no ACS Med Chem Lett (2016)

Structure–Property Basis for Solving Transporter-Mediated Efflux and Pan-Genotypic Inhibition in HCV NS5B Inhibitors

Por Yeung, Kap-Sun, Beno, Brett R., Mosure, Kathy, Zhu, Juliang, Grant-Young, Katherine A., Parcella, Kyle, Anjanappa, Prakash, Bora, Rajesh Onkardas, Selvakumar, Kumaravel, Wang, Ying-Kai, Fang, Hua, Krause, Rudolph, Rigat, Karen, Liu, Mengping, Lemm, Julie, Sheriff, Steven, Witmer, Mark, Tredup, Jeffrey, Jardel, Adam, Kish, Kevin, Parker, Dawn, Haskell, Roy, Santone, Kenneth, Meanwell, Nicholas A., Soars, Matthew G., Roberts, Susan B., Kadow, John F.
Publicado no ACS Med Chem Lett (2018)

The discovery of a pan-genotypic, primer grip inhibitor of HCV NS5B polymerase

Por Eastman, Kyle J., Parcella, Kyle, Yeung, Kap-Sun, Grant-Young, Katharine A., Zhu, Juliang, Wang, Tao, Zhang, Zhongxing, Yin, Zhiwei, Beno, Brett R., Sheriff, Steven, Kish, Kevin, Tredup, Jeffrey, Jardel, Adam G., Halan, Vivek, Ghosh, Kaushik, Parker, Dawn, Mosure, Kathy, Fang, Hua, Wang, Ying-Kai, Lemm, Julie, Zhuo, Xiaoliang, Hanumegowda, Umesh, Rigat, Karen, Donoso, Maria, Tuttle, Maria, Zvyaga, Tatyana, Haarhoff, Zuzana, Meanwell, Nicholas A., Soars, Matthew G., Roberts, Susan B., Kadow, John F.
Publicado no Medchemcomm (2017)