Potency and Resistance Analysis of Hepatitis C Virus NS5B Polymerase Inhibitor BMS-791325 on All Major Genotypes

著者: Liu, Mengping, Tuttle, Maria, Gao, Min, Lemm, Julie A.
出版年 Antimicrob Agents Chemother (2014)

Template-Dependent Initiation of Sindbis Virus RNA Replication In Vitro

著者: Lemm, Julie A., Bergqvist, Anders, Read, Carol M., Rice, Charles M.
出版事項 1998

Effect on Hepatitis C Virus Replication of Combinations of Direct-Acting Antivirals, Including NS5A Inhibitor Daclatasvir

著者: Pelosi, Lenore A., Voss, Stacey, Liu, Mengping, Gao, Min, Lemm, Julie A.
出版事項 2012

Specific Inhibition of Bovine Viral Diarrhea Virus Replicase

著者: Sun, Jin-Hua, Lemm, Julie A., O'Boyle II, Donald R., Racela, Jason, Colonno, Richard, Gao, Min
出版事項 2003

De Novo Initiation of RNA Synthesis by the RNA-Dependent RNA Polymerase (NS5B) of Hepatitis C Virus

著者: Luo, Guangxiang, Hamatake, Robert K., Mathis, Danielle M., Racela, Jason, Rigat, Karen L., Lemm, Julie, Colonno, Richard J.
出版事項 2000

Combinations of Lambda Interferon with Direct-Acting Antiviral Agents Are Highly Efficient in Suppressing Hepatitis C Virus Replication

著者: Friborg, Jacques, Levine, Steven, Chen, Chaoqun, Sheaffer, Amy K., Chaniewski, Susan, Voss, Stacey, Lemm, Julie A., McPhee, Fiona
出版事項 2013

Development of a Cell-Based High-Throughput Specificity Screen Using a Hepatitis C Virus-Bovine Viral Diarrhea Virus Dual Replicon Assay

著者: O'Boyle, Donald R., Nower, Peter T., Lemm, Julie A., Valera, Lourdes, Sun, Jin-Hua, Rigat, Karen, Colonno, Richard, Gao, Min
出版事項 2005

Randomized, Placebo-Controlled, Single-Ascending-Dose Study of BMS-791325, a Hepatitis C Virus (HCV) NS5B Polymerase Inhibitor, in HCV Genotype 1 Infection

著者: Sims, Karen D., Lemm, Julie, Eley, Timothy, Liu, Menping, Berglind, Anna, Sherman, Diane, Lawitz, Eric, Vutikullird, Apinya B., Tebas, Pablo, Gao, Min, Pasquinelli, Claudio, Grasela, Dennis M.
出版事項 2014

Identification of Hepatitis C Virus NS5A Inhibitors

著者: Lemm, Julie A., O'Boyle, Donald, Liu, Mengping, Nower, Peter T., Colonno, Richard, Deshpande, Milind S., Snyder, Lawrence B., Martin, Scott W., St. Laurent, Denis R., Serrano-Wu, Michael H., Romine, Jeffrey L., Meanwell, Nicholas A., Gao, Min
出版事項 2010

Discovery of Potent Hepatitis C Virus NS5A Inhibitors with Dimeric Structures

著者: Lemm, Julie A., Leet, John E., O'Boyle, Donald R., Romine, Jeffrey L., Huang, Xiaohua Stella, Schroeder, Daniel R., Alberts, Jeffrey, Cantone, Joseph L., Sun, Jin-Hua, Nower, Peter T., Martin, Scott W., Serrano-Wu, Michael H., Meanwell, Nicholas A., Snyder, Lawrence B., Gao, Min
出版事項 2011

Inhibitors of HCV NS5A: From Iminothiazolidinones to Symmetrical Stilbenes

著者: Romine, Jeffrey L., St. Laurent, Denis R., Leet, John E., Martin, Scott W., Serrano-Wu, Michael H., Yang, Fukang, Gao, Min, O’Boyle, Donald R, Lemm, Julie A., Sun, Jin-Hua, Nower, Peter T., Huang, Xiaohua (Stella), Deshpande, Milind S., Meanwell, Nicholas A., Snyder, Lawrence B.
出版事項 2011

Preclinical Characterization of BMS-791325, an Allosteric Inhibitor of Hepatitis C Virus NS5B Polymerase

著者: Lemm, Julie A., Liu, Mengping, Gentles, Robert G., Ding, Min, Voss, Stacey, Pelosi, Lenore A., Wang, Ying-Kai, Rigat, Karen L., Mosure, Kathleen W., Bender, John A., Knipe, Jay O., Colonno, Richard, Meanwell, Nicholas A., Kadow, John F., Santone, Kenneth S., Roberts, Susan B., Gao, Min
出版事項 2014

Chemical genetics strategy identifies an HCV NS5A inhibitor with a potent clinical effect

著者: Gao, Min, Nettles, Richard E., Belema, Makonen, Snyder, Lawrence B., Nguyen, Van N., Fridell, Robert A., Serrano-Wu, Michael H., Langley, David R., Sun, Jin-Hua, O’Boyle II, Donald R., Lemm, Julie A., Wang, Chunfu, Knipe, Jay O., Chien, Caly, Colonno, Richard J., Grasela, Dennis M., Meanwell, Nicholas A., Hamann, Lawrence G.
出版年 Nature (2010)

Improving Metabolic Stability with Deuterium: The Discovery of BMT-052, a Pan-genotypic HCV NS5B Polymerase Inhibitor

著者: Parcella, Kyle, Eastman, Kyle, Yeung, Kap-Sun, Grant-Young, Katharine A., Zhu, Juliang, Wang, Tao, Zhang, Zhongxing, Yin, Zhiwei, Parker, Dawn, Mosure, Kathy, Fang, Hua, Wang, Ying-Kai, Lemm, Julie, Zhuo, Xiaoliang, Hanumegowda, Umesh, Liu, Mengping, Rigat, Karen, Donoso, Maria, Tuttle, Maria, Zvyaga, Tatyana, Haarhoff, Zuzana, Meanwell, Nicholas A., Soars, Matthew G., Roberts, Susan B., Kadow, John F.
出版年 ACS Med Chem Lett (2017)

Structure–Property Basis for Solving Transporter-Mediated Efflux and Pan-Genotypic Inhibition in HCV NS5B Inhibitors

著者: Yeung, Kap-Sun, Beno, Brett R., Mosure, Kathy, Zhu, Juliang, Grant-Young, Katherine A., Parcella, Kyle, Anjanappa, Prakash, Bora, Rajesh Onkardas, Selvakumar, Kumaravel, Wang, Ying-Kai, Fang, Hua, Krause, Rudolph, Rigat, Karen, Liu, Mengping, Lemm, Julie, Sheriff, Steven, Witmer, Mark, Tredup, Jeffrey, Jardel, Adam, Kish, Kevin, Parker, Dawn, Haskell, Roy, Santone, Kenneth, Meanwell, Nicholas A., Soars, Matthew G., Roberts, Susan B., Kadow, John F.
出版年 ACS Med Chem Lett (2018)

The discovery of a pan-genotypic, primer grip inhibitor of HCV NS5B polymerase

著者: Eastman, Kyle J., Parcella, Kyle, Yeung, Kap-Sun, Grant-Young, Katharine A., Zhu, Juliang, Wang, Tao, Zhang, Zhongxing, Yin, Zhiwei, Beno, Brett R., Sheriff, Steven, Kish, Kevin, Tredup, Jeffrey, Jardel, Adam G., Halan, Vivek, Ghosh, Kaushik, Parker, Dawn, Mosure, Kathy, Fang, Hua, Wang, Ying-Kai, Lemm, Julie, Zhuo, Xiaoliang, Hanumegowda, Umesh, Rigat, Karen, Donoso, Maria, Tuttle, Maria, Zvyaga, Tatyana, Haarhoff, Zuzana, Meanwell, Nicholas A., Soars, Matthew G., Roberts, Susan B., Kadow, John F.
出版年 Medchemcomm (2017)