Resistance profile of the HIV-1 maturation inhibitor GSK3532795 in vitro and in a clinical study

GSK3532795 (formerly BMS955176) is a second-generation maturation inhibitor (MI) that progressed through a Phase 2b study for treatment of HIV-1 infection. Resistance development to GSK3532795 was evaluated through in vitro methods and was correlated with information obtained in a Phase 2a proof-of-...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Dicker, Ira, Zhang, Sharon, Ray, Neelanjana, Beno, Brett R., Regueiro-Ren, Alicia, Joshi, Samit, Cockett, Mark, Krystal, Mark, Lataillade, Max
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6797179/
https://ncbi.nlm.nih.gov/pubmed/31622432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0224076
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