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Resistance profile of the HIV-1 maturation inhibitor GSK3532795 in vitro and in a clinical study
GSK3532795 (formerly BMS955176) is a second-generation maturation inhibitor (MI) that progressed through a Phase 2b study for treatment of HIV-1 infection. Resistance development to GSK3532795 was evaluated through in vitro methods and was correlated with information obtained in a Phase 2a proof-of-...
Αποθηκεύτηκε σε:
Τόπος έκδοσης: | PLoS One |
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Κύριοι συγγραφείς: | , , , , , , , , |
Μορφή: | Artigo |
Γλώσσα: | Inglês |
Έκδοση: |
Public Library of Science
2019
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Θέματα: | |
Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6797179/ https://ncbi.nlm.nih.gov/pubmed/31622432 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0224076 |
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