Unraveling the Pathogenesis of MDS: The NLRP3 Inflammasome and Pyroptosis Drive the MDS Phenotype

Por Sallman, David A., Cluzeau, Thomas, Basiorka, Ashley A., List, Alan
Publicado no Front Oncol (2016)

Lenalidomide Induces Lipid Raft Assembly to Enhance Erythropoietin Receptor Signaling in Myelodysplastic Syndrome Progenitors

Por McGraw, Kathy L., Basiorka, Ashley A., Johnson, Joseph O., Clark, Justine, Caceres, Gisela, Padron, Eric, Heaton, Ruth, Ozawa, Yukiyasu, Wei, Sheng, Sokol, Lubomir, List, Alan F.
Publicado no PLoS One (2014)

Pro-inflammatory proteins S100A9 and tumor necrosis factor-α suppress erythropoietin elaboration in myelodysplastic syndromes

Por Cluzeau, Thomas, McGraw, Kathy L., Irvine, Brittany, Masala, Erico, Ades, Lionel, Basiorka, Ashley A., Maciejewski, Jaroslaw, Auberger, Patrick, Wei, Sheng, Fenaux, Pierre, Santini, Valeria, List, Alan
Publicado no Haematologica (2017)

Novel Therapeutic Approach to Improve Hematopoiesis in low risk MDS by Targeting MDSCs with The Fc-engineered CD33 Antibody BI 836858

Por Eksioglu, Erika A., Chen, Xianghong, Heider, Karl-Heinz, Rueter, Bjoern, McGraw, Kathy L., Basiorka, Ashley A., Wei, Max, Burnette, Alexis, Cheng, Pinyang, Lancet, Jeffrey, Komrokji, Rami, Djeu, Julie, List, Alan, Wei, Sheng
Publicado no Leukemia (2017)

Lenalidomide Stabilizes the Erythropoietin Receptor by Inhibiting the E3 Ubiquitin Ligase RNF41

Por Basiorka, Ashley A, McGraw, Kathy L, De Ceuninck, Leentje, Griner, Lori N, Zhang, Ling, Clark, Justine A, Caceres, Gisela, Sokol, Lubomir, Komrokji, Rami S, Reuther, Gary W, Wei, Sheng, Tavernier, Jan, List, Alan F
Publicado no Cancer Res (2016)

TP53 and MDM2 single nucleotide polymorphisms influence survival in non-del(5q) myelodysplastic syndromes

Por McGraw, Kathy L., Cluzeau, Thomas, Sallman, David A., Basiorka, Ashley A., Irvine, Brittany A., Zhang, Ling, Epling-Burnette, P.K., Rollison, Dana E., Mallo, Mar, Sokol, Lubomir, Solé, Francesc, Maciejewski, Jaroslaw, List, Alan F.
Publicado no Oncotarget (2015)

Aberrant overexpression of CD14 on granulocytes sensitizes the innate immune response in mDia1 heterozygous del(5q) MDS

Por Keerthivasan, Ganesan, Mei, Yang, Zhao, Baobing, Zhang, Ling, Harris, Chad E., Gao, Juehua, Basiorka, Ashley A., Schipma, Matthew J., McElherne, James, Yang, Jing, Verma, Amit K., Pellagatti, Andrea, Boultwood, Jacqueline, List, Alan F., Williams, David A., Ji, Peng
Publicado em 2014

TP53 suppression promotes erythropoiesis in del(5q) MDS, suggesting a targeted therapeutic strategy in lenalidomide-resistant patients

Por Caceres, Gisela, McGraw, Kathy, Yip, Bon Ham, Pellagatti, Andrea, Johnson, Joseph, Zhang, Ling, Liu, Kenian, Zhang, Lan Min, Fulp, William J., Lee, Ji-Hyun, Al Ali, Najla H., Basiorka, Ashley, Smith, Larry J., Daugherty, F. Joseph, Littleton, Neil, Wells, Richard A., Sokol, Lubomir, Wei, Sheng, Komrokji, Rami S., Boultwood, Jacqueline, List, Alan F.
Publicado em 2013

The NLRP3 inflammasome functions as a driver of the myelodysplastic syndrome phenotype

Por Basiorka, Ashley A., McGraw, Kathy L., Eksioglu, Erika A., Chen, Xianghong, Johnson, Joseph, Zhang, Ling, Zhang, Qing, Irvine, Brittany A., Cluzeau, Thomas, Sallman, David A., Padron, Eric, Komrokji, Rami, Sokol, Lubomir, Coll, Rebecca C., Robertson, Avril A. B., Cooper, Matthew A., Cleveland, John L., O’Neill, Luke A., Wei, Sheng, List, Alan F.
Publicado no Blood (2016)