Unraveling the Pathogenesis of MDS: The NLRP3 Inflammasome and Pyroptosis Drive the MDS Phenotype

Por Sallman, David A., Cluzeau, Thomas, Basiorka, Ashley A., List, Alan
Publicado no Front Oncol (2016)

Early onset hypercholesterolemia induced by the 2(nd)-generation tyrosine kinase inhibitor nilotinib in patients with chronic phase-chronic myeloid leukemia

Por Rea, Delphine, Mirault, Tristan, Cluzeau, Thomas, Gautier, Jean-François, Guilhot, François, Dombret, Hervé, Messas, Emmanuel
Publicado em 2014

Mechanisms of AXL overexpression and function in Imatinib-resistant chronic myeloid leukemia cells

Por Dufies, Maeva, Jacquel, Arnaud, Belhacene, Nathalie, Robert, Guillaume, Cluzeau, Thomas, Luciano, Fréderic, Cassuto, Jill Patrice, Raynaud, Sophie, Auberger, Patrick
Publicado em 2011

Phenotypic and genotypic characterization of azacitidine-sensitive and resistant SKM1 myeloid cell lines

Por Cluzeau, Thomas, Dubois, Alix, Jacquel, Arnaud, Luciano, Frederic, Renneville, Aline, Preudhomme, Claude, Karsenti, Jean Michel, Mounier, Nicolas, Rohrlich, Pierre, Raynaud, Sophie, Mari, Bernard, Robert, Guillaume, Auberger, Patrick
Publicado em 2014

BCL2L10 is a predictive factor for resistance to Azacitidine in MDS and AML patients

Por Cluzeau, Thomas, Robert, Guillaume, Mounier, Nicolas, Karsenti, Jean Michel, Dufies, Maeva, Puissant, Alexandre, Jacquel, Arnaud, Renneville, Aline, Preudhomme, Claude, Cassuto, Jill-Patrice, Raynaud, Sophie, Luciano, Frederic, Auberger, Patrick
Publicado em 2012

Differentiation inducing factor 3 mediates its anti-leukemic effect through ROS-dependent DRP1-mediated mitochondrial fission and induction of caspase-independent cell death

Por Dubois, Alix, Ginet, Clemence, Furstoss, Nathan, Belaid, Amine, Hamouda, Mohamed Amine, El Manaa, Wedjene, Cluzeau, Thomas, Marchetti, Sandrine, Ricci, Jean Ehrland, Jacquel, Arnaud, Luciano, Frederic, Driowya, Mohsine, Benhida, Rachid, Auberger, Patrick, Robert, Guillaume
Publicado no Oncotarget (2016)

TP53 and MDM2 single nucleotide polymorphisms influence survival in non-del(5q) myelodysplastic syndromes

Por McGraw, Kathy L., Cluzeau, Thomas, Sallman, David A., Basiorka, Ashley A., Irvine, Brittany A., Zhang, Ling, Epling-Burnette, P.K., Rollison, Dana E., Mallo, Mar, Sokol, Lubomir, Solé, Francesc, Maciejewski, Jaroslaw, List, Alan F.
Publicado no Oncotarget (2015)

The PRKAA1/AMPKα1 pathway triggers autophagy during CSF1-induced human monocyte differentiation and is a potential target in CMML

Por Obba, Sandrine, Hizir, Zoheir, Boyer, Laurent, Selimoglu-Buet, Dorothée, Pfeifer, Anja, Michel, Gregory, Hamouda, Mohamed-Amine, Gonçalvès, Diogo, Cerezo, Michael, Marchetti, Sandrine, Rocchi, Stephane, Droin, Nathalie, Cluzeau, Thomas, Robert, Guillaume, Luciano, Frederic, Robaye, Bernard, Foretz, Marc, Viollet, Benoit, Legros, Laurence, Solary, Eric, Auberger, Patrick, Jacquel, Arnaud
Publicado no Autophagy (2015)

The NLRP3 inflammasome functions as a driver of the myelodysplastic syndrome phenotype

Por Basiorka, Ashley A., McGraw, Kathy L., Eksioglu, Erika A., Chen, Xianghong, Johnson, Joseph, Zhang, Ling, Zhang, Qing, Irvine, Brittany A., Cluzeau, Thomas, Sallman, David A., Padron, Eric, Komrokji, Rami, Sokol, Lubomir, Coll, Rebecca C., Robertson, Avril A. B., Cooper, Matthew A., Cleveland, John L., O’Neill, Luke A., Wei, Sheng, List, Alan F.
Publicado no Blood (2016)

BCL-B (BCL2L10) is overexpressed in patients suffering from multiple myeloma (MM) and drives an MM-like disease in transgenic mice

Por Hamouda, Mohamed-Amine, Jacquel, Arnaud, Robert, Guillaume, Puissant, Alexandre, Richez, Valentine, Cassel, Romeo, Fenouille, Nina, Roulland, Sandrine, Gilleron, Jerome, Griessinger, Emmanuel, Dubois, Alix, Bailly-Maitre, Beatrice, Goncalves, Diogo, Mallavialle, Aude, Colosetti, Pascal, Marchetti, Sandrine, Amiot, Martine, Gomez-Bougie, Patricia, Rochet, Nathalie, Deckert, Marcel, Avet-Loiseau, Herve, Hofman, Paul, Karsenti, Jean-Michel, Jeandel, Pierre-Yves, Blin-Wakkach, Claudine, Nadel, Bertrand, Cluzeau, Thomas, Anderson, Kenneth C., Fuzibet, Jean-Gabriel, Auberger, Patrick, Luciano, Frederic
Publicado no J Exp Med (2016)