Lenalidomide Stabilizes the Erythropoietin Receptor by Inhibiting the E3 Ubiquitin Ligase RNF41

In a subset of patients with non-del(5q) myelodysplastic syndrome (MDS), lenalidomide promotes erythroid lineage competence and effective erythropoiesis. To determine the mechanism by which lenalidomide promotes erythropoiesis, we investigated its action on erythropoietin receptor (EpoR) cellular dy...

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Bibliografiska uppgifter
I publikationen:Cancer Res
Huvudupphovsmän: Basiorka, Ashley A, McGraw, Kathy L, De Ceuninck, Leentje, Griner, Lori N, Zhang, Ling, Clark, Justine A, Caceres, Gisela, Sokol, Lubomir, Komrokji, Rami S, Reuther, Gary W, Wei, Sheng, Tavernier, Jan, List, Alan F
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2016
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4911265/
https://ncbi.nlm.nih.gov/pubmed/27197154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-15-1756
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