RNF41 (Nrdp1) controls type 1 cytokine receptor degradation and ectodomain shedding

Cytokines, such as interferons, erythropoietin, leptin and most interleukins, signal through type 1 cytokine receptors and activate the canonical JAK–STAT pathway. Aberrant cytokine signalling underlies numerous pathologies and adequate, temporary receptor activation is therefore under tight control...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Wauman, Joris, De Ceuninck, Leentje, Vanderroost, Nele, Lievens, Sam, Tavernier, Jan
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Company of Biologists 2011
Gaiak:
Research Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3115735/
https://ncbi.nlm.nih.gov/pubmed/21378310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.078055
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