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Erythropoietin Receptor Signaling Is Membrane Raft Dependent
Upon erythropoietin (Epo) engagement, Epo-receptor (R) homodimerizes to activate JAK2 and Lyn, which phosphorylate STAT5. Although recent investigations have identified key negative regulators of Epo-R signaling, little is known about the role of membrane localization in controlling receptor signal...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Public Library of Science
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3317978/ https://ncbi.nlm.nih.gov/pubmed/22509308 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0034477 |
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