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Aberrant overexpression of CD14 on granulocytes sensitizes the innate immune response in mDia1 heterozygous del(5q) MDS
The myelodysplastic syndromes (MDSs) include a spectrum of stem cell malignancies characterized by an increased risk of developing acute myeloid leukemia. Heterozygous loss of chromosome 5q (del[5q]) is the most common cytogenetic abnormality in MDS. DIAPH1 is localized to 5q31 and encodes one of th...
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Main Authors: | , , , , , , , , , , , , , , , |
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格式: | Artigo |
語言: | Inglês |
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American Society of Hematology
2014
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主題: | |
在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4118486/ https://ncbi.nlm.nih.gov/pubmed/24891322 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-01-552463 |
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