Induction of Covalently Crosslinked p62 Oligomers with Reduced Binding to Polyubiquitinated Proteins by the Autophagy Inhibitor Verteporfin

von Donohue, Elizabeth, Balgi, Aruna D., Komatsu, Masaaki, Roberge, Michel
Veröffentlicht in PLoS One (2014)

Effect of small molecule eRF3 degraders on premature termination codon readthrough

von Baradaran-Heravi, Alireza, Balgi, Aruna D, Hosseini-Farahabadi, Sara, Choi, Kunho, Has, Cristina, Roberge, Michel
Veröffentlicht in Nucleic Acids Res (2021)

2-Aminothiazole-4-carboxamides Enhance Readthrough of Premature Termination Codons by Aminoglycosides

von Rabea, Safwat M., Baradaran-Heravi, Alireza, Balgi, Aruna D., Krause, Alexandra, Hosseini Farahabadi, Sara, Roberge, Michel, Grierson, David S.
Veröffentlicht in ACS Med Chem Lett (2019)

Regulation of mTORC1 Signaling by pH

von Balgi, Aruna D., Diering, Graham H., Donohue, Elizabeth, Lam, Karen K. Y., Fonseca, Bruno D., Zimmerman, Carla, Numata, Masayuki, Roberge, Michel
Veröffentlicht 2011

Screen for Chemical Modulators of Autophagy Reveals Novel Therapeutic Inhibitors of mTORC1 Signaling

von Balgi, Aruna D., Fonseca, Bruno D., Donohue, Elizabeth, Tsang, Trevor C. F., Lajoie, Patrick, Proud, Christopher G., Nabi, Ivan R., Roberge, Michel
Veröffentlicht 2009

Niclosamide Prevents the Formation of Large Ubiquitin-Containing Aggregates Caused by Proteasome Inhibition

von Gies, Esther, Wilde, Inga, Winget, Jason M., Brack, Maria, Rotblat, Barak, Novoa, Carolina Arias, Balgi, Aruna D., Sorensen, Poul H., Roberge, Michel, Mayor, Thibault
Veröffentlicht 2010

Nitazoxanide Stimulates Autophagy and Inhibits mTORC1 Signaling and Intracellular Proliferation of Mycobacterium tuberculosis

von Lam, Karen K. Y., Zheng, Xingji, Forestieri, Roberto, Balgi, Aruna D., Nodwell, Matt, Vollett, Sarah, Anderson, Hilary J., Andersen, Raymond J., Av-Gay, Yossef, Roberge, Michel
Veröffentlicht 2012

Gentamicin B1 is a minor gentamicin component with major nonsense mutation suppression activity

von Baradaran-Heravi, Alireza, Niesser, Jürgen, Balgi, Aruna D., Choi, Kunho, Zimmerman, Carla, South, Andrew P., Anderson, Hilary J., Strynadka, Natalie C., Bally, Marcel B., Roberge, Michel
Veröffentlicht in Proc Natl Acad Sci U S A (2017)

Inhibitors of the Influenza A Virus M2 Proton Channel Discovered Using a High-Throughput Yeast Growth Restoration Assay

von Balgi, Aruna D., Wang, Jun, Cheng, Daphne Y. H., Ma, Chunlong, Pfeifer, Tom A., Shimizu, Yoko, Anderson, Hilary J., Pinto, Lawrence H., Lamb, Robert A., DeGrado, William F., Roberge, Michel
Veröffentlicht 2013

Raloxifene prevents stress granule dissolution, impairs translational control and promotes cell death during hypoxia in glioblastoma cells

von Attwood, Kathleen M., Robichaud, Aaron, Westhaver, Lauren P., Castle, Elizabeth L., Brandman, David M., Balgi, Aruna D., Roberge, Michel, Colp, Patricia, Croul, Sidney, Kim, Inhwa, McCormick, Craig, Corcoran, Jennifer A., Weeks, Adrienne
Veröffentlicht in Cell Death Dis (2020)

Virtual Screening Identifies Chebulagic Acid as an Inhibitor of the M2(S31N) Viral Ion Channel and Influenza A Virus

von Duncan, Maggie C., Onguéné, Pascal Amoa, Kihara, Ibuki, Nebangwa, Derrick N., Naidu, Maya E., Williams, David E., Balgi, Aruna D., Andrae-Marobela, Kerstin, Roberge, Michel, Andersen, Raymond J., Niikura, Masahiro, Ntie-Kang, Fidele, Tietjen, Ian
Veröffentlicht in Molecules (2020)

Novel small molecules potentiate premature termination codon readthrough by aminoglycosides

von Baradaran-Heravi, Alireza, Balgi, Aruna D., Zimmerman, Carla, Choi, Kunho, Shidmoossavee, Fahimeh S., Tan, Jason S., Bergeaud, Célia, Krause, Alexandra, Flibotte, Stéphane, Shimizu, Yoko, Anderson, Hilary J., Mouly, Vincent, Jan, Eric, Pfeifer, Tom, Jaquith, James B., Roberge, Michel
Veröffentlicht in Nucleic Acids Res (2016)

Structure-Activity Analysis of Niclosamide Reveals Potential Role for Cytoplasmic pH in Control of Mammalian Target of Rapamycin Complex 1 (mTORC1) Signaling

von Fonseca, Bruno D., Diering, Graham H., Bidinosti, Michael A., Dalal, Kush, Alain, Tommy, Balgi, Aruna D., Forestieri, Roberto, Nodwell, Matt, Rajadurai, Charles V., Gunaratnam, Cynthia, Tee, Andrew R., Duong, Franck, Andersen, Raymond J., Orlowski, John, Numata, Masayuki, Sonenberg, Nahum, Roberge, Michel
Veröffentlicht 2012

Premature termination codon readthrough upregulates progranulin expression and improves lysosomal function in preclinical models of GRN deficiency

von Frew, Jonathan, Baradaran-Heravi, Alireza, Balgi, Aruna D., Wu, Xiujuan, Yan, Tyler D., Arns, Steve, Shidmoossavee, Fahimeh S., Tan, Jason, Jaquith, James B., Jansen-West, Karen R., Lynn, Francis C., Gao, Fen-Biao, Petrucelli, Leonard, Feldman, Howard H., Mackenzie, Ian R., Roberge, Michel, Nygaard, Haakon B.
Veröffentlicht in Mol Neurodegener (2020)