Induction of Covalently Crosslinked p62 Oligomers with Reduced Binding to Polyubiquitinated Proteins by the Autophagy Inhibitor Verteporfin

Por Donohue, Elizabeth, Balgi, Aruna D., Komatsu, Masaaki, Roberge, Michel
Publicado no PLoS One (2014)

2-Aminothiazole-4-carboxamides Enhance Readthrough of Premature Termination Codons by Aminoglycosides

Por Rabea, Safwat M., Baradaran-Heravi, Alireza, Balgi, Aruna D., Krause, Alexandra, Hosseini Farahabadi, Sara, Roberge, Michel, Grierson, David S.
Publicado no ACS Med Chem Lett (2019)

Regulation of mTORC1 Signaling by pH

Por Balgi, Aruna D., Diering, Graham H., Donohue, Elizabeth, Lam, Karen K. Y., Fonseca, Bruno D., Zimmerman, Carla, Numata, Masayuki, Roberge, Michel
Publicado em 2011

Screen for Chemical Modulators of Autophagy Reveals Novel Therapeutic Inhibitors of mTORC1 Signaling

Por Balgi, Aruna D., Fonseca, Bruno D., Donohue, Elizabeth, Tsang, Trevor C. F., Lajoie, Patrick, Proud, Christopher G., Nabi, Ivan R., Roberge, Michel
Publicado em 2009

Niclosamide Prevents the Formation of Large Ubiquitin-Containing Aggregates Caused by Proteasome Inhibition

Por Gies, Esther, Wilde, Inga, Winget, Jason M., Brack, Maria, Rotblat, Barak, Novoa, Carolina Arias, Balgi, Aruna D., Sorensen, Poul H., Roberge, Michel, Mayor, Thibault
Publicado em 2010

Nitazoxanide Stimulates Autophagy and Inhibits mTORC1 Signaling and Intracellular Proliferation of Mycobacterium tuberculosis

Por Lam, Karen K. Y., Zheng, Xingji, Forestieri, Roberto, Balgi, Aruna D., Nodwell, Matt, Vollett, Sarah, Anderson, Hilary J., Andersen, Raymond J., Av-Gay, Yossef, Roberge, Michel
Publicado em 2012

Gentamicin B1 is a minor gentamicin component with major nonsense mutation suppression activity

Por Baradaran-Heravi, Alireza, Niesser, Jürgen, Balgi, Aruna D., Choi, Kunho, Zimmerman, Carla, South, Andrew P., Anderson, Hilary J., Strynadka, Natalie C., Bally, Marcel B., Roberge, Michel
Publicado no Proc Natl Acad Sci U S A (2017)

Inhibitors of the Influenza A Virus M2 Proton Channel Discovered Using a High-Throughput Yeast Growth Restoration Assay

Por Balgi, Aruna D., Wang, Jun, Cheng, Daphne Y. H., Ma, Chunlong, Pfeifer, Tom A., Shimizu, Yoko, Anderson, Hilary J., Pinto, Lawrence H., Lamb, Robert A., DeGrado, William F., Roberge, Michel
Publicado em 2013

Raloxifene prevents stress granule dissolution, impairs translational control and promotes cell death during hypoxia in glioblastoma cells

Por Attwood, Kathleen M., Robichaud, Aaron, Westhaver, Lauren P., Castle, Elizabeth L., Brandman, David M., Balgi, Aruna D., Roberge, Michel, Colp, Patricia, Croul, Sidney, Kim, Inhwa, McCormick, Craig, Corcoran, Jennifer A., Weeks, Adrienne
Publicado no Cell Death Dis (2020)

Virtual Screening Identifies Chebulagic Acid as an Inhibitor of the M2(S31N) Viral Ion Channel and Influenza A Virus

Por Duncan, Maggie C., Onguéné, Pascal Amoa, Kihara, Ibuki, Nebangwa, Derrick N., Naidu, Maya E., Williams, David E., Balgi, Aruna D., Andrae-Marobela, Kerstin, Roberge, Michel, Andersen, Raymond J., Niikura, Masahiro, Ntie-Kang, Fidele, Tietjen, Ian
Publicado no Molecules (2020)

Novel small molecules potentiate premature termination codon readthrough by aminoglycosides

Por Baradaran-Heravi, Alireza, Balgi, Aruna D., Zimmerman, Carla, Choi, Kunho, Shidmoossavee, Fahimeh S., Tan, Jason S., Bergeaud, Célia, Krause, Alexandra, Flibotte, Stéphane, Shimizu, Yoko, Anderson, Hilary J., Mouly, Vincent, Jan, Eric, Pfeifer, Tom, Jaquith, James B., Roberge, Michel
Publicado no Nucleic Acids Res (2016)

Structure-Activity Analysis of Niclosamide Reveals Potential Role for Cytoplasmic pH in Control of Mammalian Target of Rapamycin Complex 1 (mTORC1) Signaling

Por Fonseca, Bruno D., Diering, Graham H., Bidinosti, Michael A., Dalal, Kush, Alain, Tommy, Balgi, Aruna D., Forestieri, Roberto, Nodwell, Matt, Rajadurai, Charles V., Gunaratnam, Cynthia, Tee, Andrew R., Duong, Franck, Andersen, Raymond J., Orlowski, John, Numata, Masayuki, Sonenberg, Nahum, Roberge, Michel
Publicado em 2012

Premature termination codon readthrough upregulates progranulin expression and improves lysosomal function in preclinical models of GRN deficiency

Por Frew, Jonathan, Baradaran-Heravi, Alireza, Balgi, Aruna D., Wu, Xiujuan, Yan, Tyler D., Arns, Steve, Shidmoossavee, Fahimeh S., Tan, Jason, Jaquith, James B., Jansen-West, Karen R., Lynn, Francis C., Gao, Fen-Biao, Petrucelli, Leonard, Feldman, Howard H., Mackenzie, Ian R., Roberge, Michel, Nygaard, Haakon B.
Publicado no Mol Neurodegener (2020)