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Regulation of mTORC1 Signaling by pH

BACKGROUND: Acidification of the cytoplasm and the extracellular environment is associated with many physiological and pathological conditions, such as intense exercise, hypoxia and tumourigenesis. Acidification affects important cellular functions including protein synthesis, growth, and proliferat...

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Detalhes bibliográficos
Main Authors: Balgi, Aruna D., Diering, Graham H., Donohue, Elizabeth, Lam, Karen K. Y., Fonseca, Bruno D., Zimmerman, Carla, Numata, Masayuki, Roberge, Michel
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3126813/
https://ncbi.nlm.nih.gov/pubmed/21738705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0021549
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