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Induction of Covalently Crosslinked p62 Oligomers with Reduced Binding to Polyubiquitinated Proteins by the Autophagy Inhibitor Verteporfin

Autophagy is a cellular catabolic process responsible for the degradation of cytoplasmic constituents, including organelles and long-lived proteins, that helps maintain cellular homeostasis and protect against various cellular stresses. Verteporfin is a benzoporphyrin derivative used clinically in p...

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Publicat a:PLoS One
Autors principals: Donohue, Elizabeth, Balgi, Aruna D., Komatsu, Masaaki, Roberge, Michel
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4262463/
https://ncbi.nlm.nih.gov/pubmed/25494214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0114964
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