The Autophagy Inhibitor Verteporfin Moderately Enhances the Antitumor Activity of Gemcitabine in a Pancreatic Ductal Adenocarcinoma Model

Pancreatic ductal adenocarcinoma (PDAC) is highly resistant to chemotherapy. It has been described as requiring elevated autophagy for growth and inhibiting autophagy has been proposed as a treatment strategy. To date, all preclinical reports and clinical trials investigating pharmacological inhibit...

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Autors principals: Donohue, Elizabeth, Thomas, Anitha, Maurer, Norbert, Manisali, Irina, Zeisser-Labouebe, Magali, Zisman, Natalia, Anderson, Hilary J., Ng, Sylvia S. W., Webb, Murray, Bally, Marcel, Roberge, Michel
Format: Artigo
Idioma:Inglês
Publicat: Ivyspring International Publisher 2013
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3781989/
https://ncbi.nlm.nih.gov/pubmed/24069069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.7030
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