Gemcitabine enhances the transport of nanovector-albumin-bound paclitaxel in gemcitabine-resistant pancreatic ductal adenocarcinoma

The mechanism for improved therapeutic efficacy of the combination therapy with albumin-bound paclitaxel (nAb-PTX) and gemcitabine (gem) for pancreatic ductal adenocarcinoma (PDAC) has been ascribed to enhanced gem transport by nAb-PTX. Here, we used an orthotopic mouse model of gem-resistant human...

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Detalles Bibliográficos
Publicado en:Cancer Lett
Main Authors: Borsoi, Carlotta, Leonard, Fransisca, Lee, Yeonju, Zaid, Mohamed, Elganainy, Dalia, Alexander, Jenolyn Francisca, Kai, Megumi, Liu, Yan Ting, Kang, Yaan, Liu, Xuewu, Koay, Eugene J., Ferrari, Mauro, Godin, Biana, Yokoi, Kenji
Formato: Artigo
Idioma:Inglês
Publicado: 2017
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5560598/
https://ncbi.nlm.nih.gov/pubmed/28687352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2017.06.026
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