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Redirecting transport of nanoparticle albumin-bound paclitaxel to macrophages enhances therapeutic efficacy against liver metastases

Current treatments for liver metastases arising from primary breast and lung cancers are minimally effective. One reason for this unfavorable outcome is that liver metastases are poorly vascularized, limiting the ability to deliver therapeutics from the systemic circulation to lesions. Seeking to en...

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Библиографические подробности
Опубликовано в: :Cancer Res
Главные авторы: Tanei, Tomonori, Leonard, Fransisca, Liu, Xuewu, Alexander, Jenolyn F., Saito, Yuki, Ferrari, Mauro, Godin, Biana, Yokoi, Kenji
Формат: Artigo
Язык:Inglês
Опубликовано: 2016
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4715951/
https://ncbi.nlm.nih.gov/pubmed/26744528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-15-1576
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