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Redirecting transport of nanoparticle albumin-bound paclitaxel to macrophages enhances therapeutic efficacy against liver metastases

Current treatments for liver metastases arising from primary breast and lung cancers are minimally effective. One reason for this unfavorable outcome is that liver metastases are poorly vascularized, limiting the ability to deliver therapeutics from the systemic circulation to lesions. Seeking to en...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Tanei, Tomonori, Leonard, Fransisca, Liu, Xuewu, Alexander, Jenolyn F., Saito, Yuki, Ferrari, Mauro, Godin, Biana, Yokoi, Kenji
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4715951/
https://ncbi.nlm.nih.gov/pubmed/26744528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-15-1576
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