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Enhanced performance of macrophage-encapsulated nanoparticle albumin-bound-paclitaxel in hypo-perfused cancer lesions

Hypovascularization in tumors such as liver metastases originating from breast and other organs correlates with poor chemotherapeutic response and higher mortality. Poor prognosis is linked to impaired transport of both low- and high-molecular weight drugs into the lesions and to high washout rate....

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Detalhes bibliográficos
Publicado no:Nanoscale
Main Authors: Leonard, Fransisca, Curtis, Louis T., Yesantharao, Pooja, Tanei, Tomonori, Alexander, Jenolyn F., Wu, Min, Lowengrub, John, Liu, Xuewu, Ferrari, Mauro, Yokoi, Kenji, Frieboes, Hermann B., Godin, Biana
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4919151/
https://ncbi.nlm.nih.gov/pubmed/26818212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5nr07796f
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