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Enhanced performance of macrophage-encapsulated nanoparticle albumin-bound-paclitaxel in hypo-perfused cancer lesions

Hypovascularization in tumors such as liver metastases originating from breast and other organs correlates with poor chemotherapeutic response and higher mortality. Poor prognosis is linked to impaired transport of both low- and high-molecular weight drugs into the lesions and to high washout rate....

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Bibliografski detalji
Izdano u:Nanoscale
Glavni autori: Leonard, Fransisca, Curtis, Louis T., Yesantharao, Pooja, Tanei, Tomonori, Alexander, Jenolyn F., Wu, Min, Lowengrub, John, Liu, Xuewu, Ferrari, Mauro, Yokoi, Kenji, Frieboes, Hermann B., Godin, Biana
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4919151/
https://ncbi.nlm.nih.gov/pubmed/26818212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5nr07796f
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