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Effect of small molecule eRF3 degraders on premature termination codon readthrough
Premature termination codon (PTC) readthrough is considered a potential treatment for genetic diseases caused by nonsense mutations. High concentrations of aminoglycosides induce low levels of PTC readthrough but also elicit severe toxicity. Identifying compounds that enhance PTC readthrough by amin...
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| Publicado no: | Nucleic Acids Res |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8053119/ https://ncbi.nlm.nih.gov/pubmed/33764477 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkab194 |
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