miR-34 – a microRNA replacement therapy is headed to the clinic

Por Bader, Andreas G.
Publicado em 2012

miR-888: Hit it when you see it!

Por Bader, Andreas G
Publicado em 2014

Inhibition of Protein Synthesis by Y Box-Binding Protein 1 Blocks Oncogenic Cell Transformation

Por Bader, Andreas G., Vogt, Peter K.
Publicado em 2005

The Promise of MicroRNA Replacement Therapy

Por Bader, Andreas G., Brown, David, Winkler, Matthew
Publicado em 2010

In-Depth Analysis Shows Synergy between Erlotinib and miR-34a

Por Zhao, Jane, Kelnar, Kevin, Bader, Andreas G.
Publicado em 2014

Phosphatidylinositol 3-kinase mutations identified in human cancer are oncogenic

Por Kang, Sohye, Bader, Andreas G., Vogt, Peter K.
Publicado em 2005

Cancer-specific mutations in PIK3CA are oncogenic in vivo

Por Bader, Andreas G., Kang, Sohye, Vogt, Peter K.
Publicado em 2006

TP53-independent Function of miR-34a via HDAC1 and p21(CIP1/WAF1)

Por Zhao, Jane, Lammers, Paul, Torrance, Chris J, Bader, Andreas G
Publicado em 2013

JAC, a direct target of oncogenic transcription factor Jun, is involved in cell transformation and tumorigenesis

Por Hartl, Markus, Reiter, Fritz, Bader, Andreas G., Castellazzi, Marc, Bister, Klaus
Publicado em 2001

Quantification of Therapeutic miRNA Mimics in Whole Blood from Nonhuman Primates

Por Kelnar, Kevin, Peltier, Heidi J., Leatherbury, Neil, Stoudemire, Jay, Bader, Andreas G.
Publicado em 2014

Y box-binding protein 1 induces resistance to oncogenic transformation by the phosphatidylinositol 3-kinase pathway

Por Bader, Andreas G., Felts, Katherine A., Jiang, Ning, Chang, Hwai Wen, Vogt, Peter K.
Publicado em 2003

Development of a lung cancer therapeutic based on the tumor suppressor microRNA-34

Por Wiggins, Jason F., Ruffino, Lynnsie, Kelnar, Kevin, Omotola, Michael, Patrawala, Lubna, Brown, David, Bader, Andreas G.
Publicado em 2010

Phosphatidylinositol 3-kinase (PI3K): The Oncoprotein

Por Vogt, Peter K., Hart, Jonathan R., Gymnopoulos, Marco, Jiang, Hao, Kang, Sohye, Bader, Andreas G., Zhao, Li, Denley, Adam
Publicado em 2011

Systemic Delivery of Tumor Suppressor microRNA Mimics Using a Neutral Lipid Emulsion Inhibits Lung Tumors in Mice

Por Trang, Phong, Wiggins, Jason F, Daige, Christopher L, Cho, Chris, Omotola, Michael, Brown, David, Weidhaas, Joanne B, Bader, Andreas G, Slack, Frank J
Publicado em 2011

A combinatorial microRNA therapeutics approach to suppressing non-small cell lung cancer

Por Kasinski, Andrea L., Kelnar, Kevin, Stahlhut, Carlos, Orellana, Esteban, Zhao, Jane, Shimer, Eliot, Dysart, Sarah, Chen, Xiaowei, Bader, Andreas G., Slack, Frank J.
Publicado no Oncogene (2014)

Phase I study of MRX34, a liposomal miR-34a mimic, administered twice weekly in patients with advanced solid tumors

Por Beg, Muhammad S., Brenner, Andrew J., Sachdev, Jasgit, Borad, Mitesh, Kang, Yoon-Koo, Stoudemire, Jay, Smith, Susan, Bader, Andreas G., Kim, Sinil, Hong, David S.
Publicado no Invest New Drugs (2016)

Systemic Delivery of Synthetic MicroRNA-16 Inhibits the Growth of Metastatic Prostate Tumors via Downregulation of Multiple Cell-cycle Genes

Por Takeshita, Fumitaka, Patrawala, Lubna, Osaki, Mitsuhiko, Takahashi, Ryou-u, Yamamoto, Yusuke, Kosaka, Nobuyoshi, Kawamata, Masaki, Kelnar, Kevin, Bader, Andreas G., Brown, David, Ochiya, Takahiro
Publicado em 2009

Regression of murine lung tumors by the let-7 microRNA

Por Trang, Phong, Medina, Pedro P., Wiggins, Jason F., Ruffino, Lynnsie, Kelnar, Kevin, Omotola, Michael, Homer, Robert, Brown, David, Bader, Andreas G., Weidhaas, Joanne B., Slack, Frank J.
Publicado em 2009

Identification of miR-34a as a potent inhibitor of prostate cancer progenitor cells and metastasis by directly repressing CD44

Por Liu, Can, Kelnar, Kevin, Liu, Bigang, Chen, Xin, Calhoun-Davis, Tammy, Li, Hangwen, Patrawala, Lubna, Yan, Hong, Jeter, Collene, Honorio, Sofia, Wiggins, Jason F., Bader, Andreas G., Fagin, Randy, Brown, David, Tang, Dean G.
Publicado em 2011

In Vivo Delivery of miR-34a Sensitizes Lung Tumors to Radiation Through RAD51 Regulation

Por Cortez, Maria Angelica, Valdecanas, David, Niknam, Sharareh, Peltier, Heidi J, Diao, Lixia, Giri, Uma, Komaki, Ritsuko, Calin, George A, Gomez, Daniel R, Chang, Joe Y, Heymach, John Victor, Bader, Andreas G, Welsh, James William
Publicado no Mol Ther Nucleic Acids (2015)