Regression of murine lung tumors by the let-7 microRNA

MicroRNAs (miRNAs) have recently emerged as an important new class of cellular regulators that control various cellular processes and are implicated in human diseases, including cancer. Here, we show that loss of let-7 function enhances lung tumor formation in vivo, strongly supporting the hypothesi...

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Main Authors: Trang, Phong, Medina, Pedro P., Wiggins, Jason F., Ruffino, Lynnsie, Kelnar, Kevin, Omotola, Michael, Homer, Robert, Brown, David, Bader, Andreas G., Weidhaas, Joanne B., Slack, Frank J.
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2841713/
https://ncbi.nlm.nih.gov/pubmed/19966857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2009.445
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