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Regression of murine lung tumors by the let-7 microRNA

MicroRNAs (miRNAs) have recently emerged as an important new class of cellular regulators that control various cellular processes and are implicated in human diseases, including cancer. Here, we show that loss of let-7 function enhances lung tumor formation in vivo, strongly supporting the hypothesi...

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Detalhes bibliográficos
Main Authors: Trang, Phong, Medina, Pedro P., Wiggins, Jason F., Ruffino, Lynnsie, Kelnar, Kevin, Omotola, Michael, Homer, Robert, Brown, David, Bader, Andreas G., Weidhaas, Joanne B., Slack, Frank J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2841713/
https://ncbi.nlm.nih.gov/pubmed/19966857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2009.445
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