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Development of a lung cancer therapeutic based on the tumor suppressor microRNA-34

Tumor suppressor microRNAs (miRNAs) provide a new opportunity to treat cancer. This approach, “miRNA replacement therapy”, is based on the concept that the re-introduction of miRNAs depleted in cancer cells reactivates cellular pathways that drive a therapeutic response. Here, we describe the develo...

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Detalhes bibliográficos
Main Authors: Wiggins, Jason F., Ruffino, Lynnsie, Kelnar, Kevin, Omotola, Michael, Patrawala, Lubna, Brown, David, Bader, Andreas G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2913706/
https://ncbi.nlm.nih.gov/pubmed/20570894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-0655
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