In Vivo Delivery of miR-34a Sensitizes Lung Tumors to Radiation Through RAD51 Regulation

MiR-34a, an important tumor-suppressing microRNA, is downregulated in several types of cancer; loss of its expression has been linked with unfavorable clinical outcomes in non-small-cell lung cancer (NSCLC), among others. MiR-34a represses several key oncogenic proteins, and a synthetic mimic of miR...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Mol Ther Nucleic Acids
Autori principali: Cortez, Maria Angelica, Valdecanas, David, Niknam, Sharareh, Peltier, Heidi J, Diao, Lixia, Giri, Uma, Komaki, Ritsuko, Calin, George A, Gomez, Daniel R, Chang, Joe Y, Heymach, John Victor, Bader, Andreas G, Welsh, James William
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2015
Soggetti:
Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5014539/
https://ncbi.nlm.nih.gov/pubmed/26670277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtna.2015.47
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi