Therapeutic Delivery of miR-200c Enhances Radiosensitivity in Lung Cancer

The microRNA (miR)-200s and their negative regulator ZEB1 have been extensively studied in the context of the epithelial–mesenchymal transition. Loss of miR-200s has been shown to enhance cancer aggressiveness and metastasis, whereas replacement of miR-200 miRNAs has been shown to inhibit cell growt...

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Bibliographische Detailangaben
Veröffentlicht in:Mol Ther
Hauptverfasser: Cortez, Maria Angelica, Valdecanas, David, Zhang, Xiaochun, Zhan, Yanai, Bhardwaj, Vikas, Calin, George A, Komaki, Ritsuko, Giri, Dipak K, Quini, Caio C, Wolfe, Tatiana, Peltier, Heidi J, Bader, Andreas G, Heymach, John V, Meyn, Raymond E, Welsh, James W
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2014
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4435581/
https://ncbi.nlm.nih.gov/pubmed/24791940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2014.79
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