C-Met Inhibitor MK-8003 Radiosensitizes c-Met–Expressing Non-Small Cell Lung Cancer Cells with Radiation-Induced c-Met–Expression

INTRODUCTION: The radiation doses used to treat unresectable lung cancer are often limited by the proximity of normal tissues. Overexpression of c-Met, a receptor tyrosine kinase occurs in about half of non-small cell lung cancers (NSCLCs) and has been associated with resistance to radiation therapy...

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Hlavní autoři: Bhardwaj, Vikas, Zhan, Yanai, Cortez, Maria Angelica, Ang, K. Kian, Molkentine, David, Munshi, Anupama, Raju, Uma, Komaki, Ritsuko, Heymach, John V., Welsh, James
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3399033/
https://ncbi.nlm.nih.gov/pubmed/22617250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/JTO.0b013e318257cc89
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