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C-Met Inhibitor MK-8003 Radiosensitizes c-Met–Expressing Non-Small Cell Lung Cancer Cells with Radiation-Induced c-Met–Expression
INTRODUCTION: The radiation doses used to treat unresectable lung cancer are often limited by the proximity of normal tissues. Overexpression of c-Met, a receptor tyrosine kinase occurs in about half of non-small cell lung cancers (NSCLCs) and has been associated with resistance to radiation therapy...
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| Autori principali: | , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3399033/ https://ncbi.nlm.nih.gov/pubmed/22617250 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/JTO.0b013e318257cc89 |
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